Interactor 1: NPHP1 (O15259)
Nephrocystin-1 (Juvenile nephronophthisis 1 protein)
Gene: NPHP1

Interactor 2: FAK2 (Q14289)
Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)
Gene: PTK2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.90 0.765

The method score is based on:

Property Details
Experiments 11493697, 21357692
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0007165 - signal transduction
Homologous interactions 0

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Last updated: 15 Jul 2024