HitPredict

Interactor 1: MK13 (O15264)
Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)
Gene: MAPK13

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	15632108, 9199504
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 758
+	Hs
		497100 MK14_HUMAN (1-361): 1.15e-149: 427: 60.22		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496628 MK12_HUMAN (2-352): 1.77e-145: 417: 65.91		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496330 CDK2_HUMAN (22-320): 5.41e-146: 416: 37.26		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496357 MK03_HUMAN (12-354): 1.25e-144: 415: 43.43		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496371 MK01_HUMAN (12-355): 3.63e-144: 414: 42.74		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497084 MK11_HUMAN (1-349): 3.5e-144: 414: 60.57		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581973 MK01_RAT (12-355): 3.04e-144: 414: 42.74		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94196 MK01_RAT (12-355): 3.04e-144: 414: 42.74		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		497992 MK01_MOUSE (12-355): 3.04e-144: 414: 42.74		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		496513 MK08_HUMAN (5-349): 1.76e-109: 328: 46.81		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496514 MK09_HUMAN (9-349): 2.13e-109: 328: 47.19		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496629 MK10_HUMAN (9-348): 8.79e-109: 327: 47.61		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		1082653 MK14_HUMAN (1-361): 1.15e-149: 427: 60.22		MUC12_HUMAN (15-752): 1.81e-12: 73.5: 8.54
+	Rn
		926487 MK01_RAT (12-355): 3.04e-144: 414: 42.74		SYNJ1_RAT (72-557): 4.95e-13: 75: 12.10
+	Hs
		1082593 MK14_HUMAN (1-361): 1.15e-149: 427: 60.22		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Rn
		926474 MK01_RAT (12-355): 3.04e-144: 414: 42.74		MAP4_RAT (60-757): 1.97e-10: 66.6: 8.17
+	Rn
		600416 MK03_RAT (15-354): 1.42e-143: 413: 43.23		MAP4_RAT (60-757): 1.97e-10: 66.6: 8.17