Interactor 1: SPTC1 (O15269)
Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1)
Gene: SPTLC1
Interactor 2: SPTSB (Q8NFR3)
Serine palmitoyltransferase small subunit B (Protein ADMP) (Small subunit of serine palmitoyltransferase B) (ssSPTb)
Gene: SPTSSB
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.34 | 1.00 | 0.590 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19416851 |
| Identification Methods | ubiquitin reconstruction |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aminotran_1_2~SPT_ssu-like |
| Common GO terms | GO:0004758 - serine C-palmitoyltransferase activity GO:0005789 - endoplasmic reticulum membrane GO:0017059 - serine palmitoyltransferase complex GO:0030148 - sphingolipid biosynthetic process GO:0046512 - sphingosine biosynthetic process and 1 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
