Protein: AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (Calcium pump 3)

Gene: AT2A3, ATP2A3
Organism: Homo sapiens
Interactions: 234
UniProt ID: Q93084

Gene Ontology (top 5):
GO:0005246 - calcium channel regulator activity
GO:0005388 - P-type calcium transporter activity
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598166

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

3

16

High-throughput

0.847

High

174027

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

2

16

High-throughput

0.789

High

1270278

BT2A1
Butyrophilin subfamily 2 member A1

3

7

High-throughput

0.770

High

1293884

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

4

High-throughput

0.726

High

1324377

ABD12
Lysophosphatidylserine lipase ABHD12

1

2

High-throughput

0.691

High

63885

5HT3E
5-hydroxytryptamine receptor 3E

3

1

High-throughput

0.667

High

212463

SPIT2
Kunitz-type protease inhibitor 2

3

3

High-throughput

0.667

High

476011

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

3

4

High-throughput

0.667

High

1372378

CGRF1
Cell growth regulator with RING finger domain protein 1

3

1

High-throughput

0.667

High

1372432

SRPRB
Signal recognition particle receptor subunit beta

3

11

High-throughput

0.667

High

946580

EVA1C
Protein eva-1 homolog C

3

0

High-throughput

0.638

High

1351222

MCLN3
Mucolipin-3

3

0

High-throughput

0.638

High

303710

CYTF
Cystatin-F

2

2

High-throughput

0.628

High

648832

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

6

High-throughput

0.628

High

829911

PMEL
Melanocyte protein PMEL

2

5

High-throughput

0.628

High

1180859

S4A8
Electroneutral sodium bicarbonate exchanger 1

2

4

High-throughput

0.628

High

1243380

LRC8B
Volume-regulated anion channel subunit LRRC8B

2

2

High-throughput

0.628

High

1288326

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

2

12

High-throughput

0.628

High

1332794

FNDC5
Fibronectin type III domain-containing protein 5

2

2

High-throughput

0.628

High

1359078

TMED6
Transmembrane emp24 domain-containing protein 6

2

6

High-throughput

0.628

High

1372379

KCNS3
Delayed-rectifier potassium channel regulatory subunit KCNS3

2

6

High-throughput

0.628

High

1372403

I17RB
Interleukin-17 receptor B

2

1

High-throughput

0.628

High

1372419

PCDGG
Protocadherin gamma-B4

2

9

High-throughput

0.628

High

1372422

ENTP4
Ectonucleoside triphosphate diphosphohydrolase 4

2

8

High-throughput

0.628

High

1372428

PCDBB
Protocadherin beta-11

2

8

High-throughput

0.628

High

1249759

BTNL3
Butyrophilin-like protein 3

1

4

High-throughput

0.618

High

1249823

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.618

High

1372408

PD1L1
Programmed cell death 1 ligand 1

1

14

High-throughput

0.618

High

1212109

TRML2
Trem-like transcript 2 protein

3

1

High-throughput

0.609

High

1372364

TSN17
Tetraspanin-17

3

11

High-throughput

0.609

High

1353075

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

2

0

High-throughput

0.602

High

564165

CFTR
Cystic fibrosis transmembrane conductance regulator

2

10

High-throughput

0.601

High

1156941

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

6

High-throughput

0.574

High

1157429

GBRA6
Gamma-aminobutyric acid receptor subunit alpha-6

2

2

High-throughput

0.574

High

1308125

SYT12
Synaptotagmin-12

2

1

High-throughput

0.574

High

1332610

I17RC
Interleukin-17 receptor C

2

2

High-throughput

0.574

High

1372386

LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1

2

6

High-throughput

0.574

High

1372431

PCDA3
Protocadherin alpha-3

2

9

High-throughput

0.574

High

122636

UBXN8
UBX domain-containing protein 8

1

8

High-throughput

0.536

High

182706

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.536

High

184488

SURF4
Surfeit locus protein 4

1

2

High-throughput

0.536

High

191228

TLR3
Toll-like receptor 3

1

9

High-throughput

0.536

High

219450

S26A4
Pendrin

1

2

High-throughput

0.536

High

225379

ERD23
ER lumen protein-retaining receptor 3

1

5

High-throughput

0.536

High

249503

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

3

High-throughput

0.536

High

253875

TPST2
Protein-tyrosine sulfotransferase 2

1

3

High-throughput

0.536

High

270039

XYLK
Glycosaminoglycan xylosylkinase

1

2

High-throughput

0.536

High

270470

FZD7
Frizzled-7

1

1

High-throughput

0.536

High

276976

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

1

High-throughput

0.536

High

297240

PRAF3
PRA1 family protein 3

1

5

High-throughput

0.536

High

327396

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.536

High

339555

ACSL3
Fatty acid CoA ligase Acsl3

1

3

High-throughput

0.536

High

575759

IL1R1
Interleukin-1 receptor type 1

1

2

High-throughput

0.536

High

665002

ERD21
ER lumen protein-retaining receptor 1

1

5

High-throughput

0.536

High

669045

FPR2
N-formyl peptide receptor 2

1

20

High-throughput

0.536

High

683304

TNR5
Tumor necrosis factor receptor superfamily member 5

1

11

High-throughput

0.536

High

701884

ABCD3
ATP-binding cassette sub-family D member 3

1

12

High-throughput

0.536

High

723700

NTR1
Neurotensin receptor type 1

1

19

High-throughput

0.536

High

755364

ABCD1
ATP-binding cassette sub-family D member 1

1

8

High-throughput

0.536

High

755505

ERD22
ER lumen protein-retaining receptor 2

1

5

High-throughput

0.536

High

835001

S19A1
Reduced folate transporter

1

2

High-throughput

0.536

High

909126

NEK4
Serine/threonine-protein kinase Nek4

1

4

High-throughput

0.536

High

941952

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.536

High

1085360

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

9

High-throughput

0.536

High

1088783

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

3

High-throughput

0.536

High

1101764

PTK7
Inactive tyrosine-protein kinase 7

1

9

High-throughput

0.536

High

1105861

TMED1
Transmembrane emp24 domain-containing protein 1

1

7

High-throughput

0.536

High

1106805

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

1

High-throughput

0.536

High

1116831

AVR2B
Activin receptor type-2B

1

3

High-throughput

0.536

High

1126334

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

1143652

NOMO1
BOS complex subunit NOMO1

1

3

High-throughput

0.536

High

1144649

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

3

High-throughput

0.536

High

1147816

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.536

High

1157385

EXT1
Exostosin-1

1

3

High-throughput

0.536

High

1179666

D19L1
Protein C-mannosyl-transferase DPY19L1

1

1

High-throughput

0.536

High

1185821

PTHD3
Patched domain-containing protein 3

1

5

High-throughput

0.536

High

1198381

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

9

High-throughput

0.536

High

1203756

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1209981

TM201
Transmembrane protein 201

1

1

High-throughput

0.536

High

1218849

GP107
Protein GPR107

1

1

High-throughput

0.536

High

1228361

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

1

High-throughput

0.536

High

1233649

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

5

High-throughput

0.536

High

1240921

S27A4
Long-chain fatty acid transport protein 4

1

4

High-throughput

0.536

High

1248538

LCTL
Lactase-like protein

1

1

High-throughput

0.536

High

1251301

HACD2
Very-long-chain

1

4

High-throughput

0.536

High

1251734

CERS6
Ceramide synthase 6

1

2

High-throughput

0.536

High

1270592

COX15
Heme A synthase COX15

1

2

High-throughput

0.536

High

1273263

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

2

High-throughput

0.536

High

1275384

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

2

High-throughput

0.536

High

1281259

TMED4
Transmembrane emp24 domain-containing protein 4

1

4

High-throughput

0.536

High

1286497

SCD5
Stearoyl-CoA desaturase 5

1

3

High-throughput

0.536

High

1288640

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

9

High-throughput

0.536

High

1293346

CHSS1
Chondroitin sulfate synthase 1

1

5

High-throughput

0.536

High

1293971

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

High-throughput

0.536

High

1309862

TEX2
Testis-expressed protein 2

1

1

High-throughput

0.536

High

1312326

MIRO1
Mitochondrial Rho GTPase 1

1

20

High-throughput

0.536

High

1326476

CQ078
Uncharacterized protein C17orf78

1

2

High-throughput

0.536

High

1335144

LEMD2
LEM domain-containing protein 2

1

3

High-throughput

0.536

High

1337764

ACV1C
Activin receptor type-1C

1

3

High-throughput

0.536

High

1349080

F174A
Membrane protein FAM174A

1

4

High-throughput

0.536

High

1350026

SPP2B
Signal peptide peptidase-like 2B

1

4

High-throughput

0.536

High

1357243

S38A5
Sodium-coupled neutral amino acid transporter 5

1

2

High-throughput

0.536

High

1362072

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

2

High-throughput

0.536

High

1363194

AQP3
Aquaporin-3

1

1

High-throughput

0.536

High

1363514

PIEZ1
Piezo-type mechanosensitive ion channel component 1

1

4

High-throughput

0.536

High

1372359

TM143
Transmembrane protein 143

1

1

High-throughput

0.536

High

1372369

CLP1L
Lipid scramblase CLPTM1L

1

3

High-throughput

0.536

High

1372370

B3GT6
Beta-1,3-galactosyltransferase 6

1

3

High-throughput

0.536

High

1372371

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

4

High-throughput

0.536

High

1372375

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

2

High-throughput

0.536

High

1372377

SEC62
Translocation protein SEC62

1

3

High-throughput

0.536

High

1372382

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

1

High-throughput

0.536

High

1372383

ELOV1
Very long chain fatty acid elongase 1

1

3

High-throughput

0.536

High

1372389

UN93B
Protein unc-93 homolog B1

1

3

High-throughput

0.536

High

1372390

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1372391

GHITM
Growth hormone-inducible transmembrane protein

1

1

High-throughput

0.536

High

1372392

KCNF1
Voltage-gated potassium channel regulatory subunit KCNF1

1

6

High-throughput

0.536

High

1372396

RXFP1
Relaxin receptor 1

1

11

High-throughput

0.536

High

1372401

TLR8
Toll-like receptor 8

1

2

High-throughput

0.536

High

1372402

PCDBG
Protocadherin beta-16

1

8

High-throughput

0.536

High

1372404

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

2

High-throughput

0.536

High

1372406

T161A
Transmembrane protein 161A

1

1

High-throughput

0.536

High

1372407

CISD1
CDGSH iron-sulfur domain-containing protein 1

1

2

High-throughput

0.536

High

1372409

VAPA
Vesicle-associated membrane protein-associated protein A

1

6

High-throughput

0.536

High

1372412

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

4

High-throughput

0.536

High

1372413

EXTL2
Exostosin-like 2

1

3

High-throughput

0.536

High

1372415

CLC2D
C-type lectin domain family 2 member D

1

9

High-throughput

0.536

High

1372416

NB5R1
NADH-cytochrome b5 reductase 1

1

7

High-throughput

0.536

High

1372417

CAH14
Carbonic anhydrase 14

1

3

High-throughput

0.536

High

1372418

TMCO1
Calcium load-activated calcium channel

1

1

High-throughput

0.536

High

1372421

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

6

High-throughput

0.536

High

1372423

EXOG
Nuclease EXOG, mitochondrial

1

1

High-throughput

0.536

High

1372425

MAN1
Inner nuclear membrane protein Man1

1

5

High-throughput

0.536

High

1372426

TMED5
Transmembrane emp24 domain-containing protein 5

1

7

High-throughput

0.536

High

1372427

PCDB5
Protocadherin beta-5

1

8

High-throughput

0.536

High

650891

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.515

High

1372388

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

1

High-throughput

0.515

High

788981

TGFR2
TGF-beta receptor type-2

1

3

High-throughput

0.515

High

139107

FAAH1
Fatty-acid amide hydrolase 1

1

0

High-throughput

0.513

High

166973

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.513

High

249263

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

0

High-throughput

0.513

High

821685

TPOR
Thrombopoietin receptor

1

0

High-throughput

0.513

High

1238075

CP4FN
Ultra-long-chain fatty acid omega-hydroxylase

1

0

High-throughput

0.513

High

1290217

GP180
Integral membrane protein GPR180

1

0

High-throughput

0.513

High

1352481

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.513

High

1372368

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.513

High

1372376

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.513

High

1372384

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

0

High-throughput

0.513

High

1372385

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

139284

UPK2
Uroplakin-2

1

2

High-throughput

0.489

High

166005

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.489

High

175476

AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1

1

2

High-throughput

0.489

High

277031

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

8

High-throughput

0.489

High

349518

TSN15
Tetraspanin-15

1

11

High-throughput

0.489

High

351938

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.489

High

462793

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

1

High-throughput

0.489

High

583588

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

5

High-throughput

0.489

High

638224

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.489

High

640441

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

20

High-throughput

0.489

High

689841

CD27
CD27 antigen

1

10

High-throughput

0.489

High

749373

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

1

High-throughput

0.489

High

814838

CUX1
Homeobox protein cut-like 1

1

5

High-throughput

0.489

High

820570

GPV
Platelet glycoprotein V

1

11

High-throughput

0.489

High

833849

P2RY2
P2Y purinoceptor 2

1

20

High-throughput

0.489

High

907046

CCR6
C-C chemokine receptor type 6

1

20

High-throughput

0.489

High

936100

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.489

High

1101294

SLAF1
Signaling lymphocytic activation molecule

1

7

High-throughput

0.489

High

1101614

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

20

High-throughput

0.489

High

1180946

HFE
Hereditary hemochromatosis protein

1

4

High-throughput

0.489

High

1280015

CE024
UPF0461 protein C5orf24

1

2

High-throughput

0.489

High

1291853

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.489

High

1309643

GLBL2
Beta-galactosidase-1-like protein 2

1

1

High-throughput

0.489

High

1311639

KIBRA
Protein KIBRA

1

4

High-throughput

0.489

High

1328750

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

5

High-throughput

0.489

High

1333756

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.489

High

1372358

F162A
Protein FAM162A

1

2

High-throughput

0.489

High

1372360

TLCD1
TLC domain-containing protein 1

1

1

High-throughput

0.489

High

1372361

HDA11
Histone deacetylase 11

1

3

High-throughput

0.489

High

1372362

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

1

High-throughput

0.489

High

1372367

FACR2
Fatty acyl-CoA reductase 2

1

4

High-throughput

0.489

High

1372380

S2533
Solute carrier family 25 member 33

1

3

High-throughput

0.489

High

1372387

RSH6A
Radial spoke head protein 6 homolog A

1

1

High-throughput

0.489

High

1372395

LPAR2
Lysophosphatidic acid receptor 2

1

20

High-throughput

0.489

High

1372397

GPR35
G-protein coupled receptor 35

1

20

High-throughput

0.489

High

1372398

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.489

High

1372405

GP173
Probable G-protein coupled receptor 173

1

9

High-throughput

0.489

High

1372410

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

2

High-throughput

0.489

High

1372414

ARMX3
Armadillo repeat-containing X-linked protein 3

1

1

High-throughput

0.489

High

1372420

PCDAC
Protocadherin alpha-12

1

9

High-throughput

0.489

High

1372424

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

3

High-throughput

0.489

High

1372429

PCDGE
Protocadherin gamma-B2

1

8

High-throughput

0.489

High

1372430

PCDG5
Protocadherin gamma-A5

1

8

High-throughput

0.489

High

1372433

GPR45
Probable G-protein coupled receptor 45

1

20

High-throughput

0.489

High

1372434

HCFC2
Host cell factor 2

1

1

High-throughput

0.489

High

409466

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

3

High-throughput

0.479

High

522120

BCL2
Apoptosis regulator Bcl-2

1

1

Small-scale

0.479

High

594073

NCK1
SH2/SH3 adapter protein NCK1

1

2

High-throughput

0.479

High

667967

CDK2
Cyclin-dependent kinase 2

1

3

High-throughput

0.479

High

1372365

VMP1
Vacuole membrane protein 1

1

2

Small-scale

0.479

High

1372411

WRP73
WD repeat-containing protein WRAP73

1

2

High-throughput

0.470

High

380570

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

10

High-throughput

0.445

High

410984

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

8

High-throughput

0.445

High

876434

EAA4
Excitatory amino acid transporter 4

1

1

High-throughput

0.445

High

1335664

MOT11
Monocarboxylate transporter 11

1

10

High-throughput

0.445

High

218584

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

343272

ERR2
Steroid hormone receptor ERR2

1

7

High-throughput

0.437

High

506635

GPHRB
Golgi pH regulator B

1

3

High-throughput

0.437

High

587515

TFE2
Transcription factor E2-alpha

1

1

High-throughput

0.437

High

765774

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.437

High

1100194

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.437

High

1338311

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

1368032

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.437

High

1372393

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1372394

BRF2
Transcription factor IIIB 50 kDa subunit

1

1

High-throughput

0.437

High

1372400

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.437

High

85386

GPHRA
Golgi pH regulator A

1

3

High-throughput

0.407

High

1119450

CASP
Protein CASP

1

7

High-throughput

0.407

High

1227203

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.407

High

1372373

B3A4
Anion exchange protein 4

1

4

High-throughput

0.407

High

219652

B2L11
Bcl-2-like protein 11

3

0

High-throughput

0.347

High

1372363

ASIC4
Acid-sensing ion channel 4

2

0

High-throughput

0.328

High

1329536

IQCF1
IQ domain-containing protein F1

2

0

High-throughput

0.318

High

49810

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

295357

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.279

Low

690718

AOFB
Amine oxidase [flavin-containing] B

1

0

High-throughput

0.279

Low

760484

SDC2
Syndecan-2

1

0

High-throughput

0.279

Low

1140228

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.279

Low

1141523

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.279

Low

1329599

I22R1
Interleukin-22 receptor subunit alpha-1

1

0

High-throughput

0.279

Low

1372366

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.279

Low

1372372

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

1372374

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

0

High-throughput

0.279

Low

1372381

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.279

Low

1372399

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025