Interactor 1: SPTC1 (O15269)
Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1)
Gene: SPTLC1
Interactor 2: SPTC3 (Q9NUV7)
Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3)
Gene: SPTLC3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.680 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19416851 |
| Identification Methods | ubiquitin reconstruction, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aminotran_1_2~Aminotran_1_2 |
| Common GO terms | GO:0004758 - serine C-palmitoyltransferase activity GO:0005789 - endoplasmic reticulum membrane GO:0017059 - serine palmitoyltransferase complex GO:0030148 - sphingolipid biosynthetic process GO:0030170 - pyridoxal phosphate binding and 2 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
