HitPredict

Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	32994395, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1046 Hs			1 483
+	Hs
		174631 OGT1_HUMAN (1-1046): 0: 969: 100.00		CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03
+	Hs
		174723 OGT1_HUMAN (1-1046): 0: 969: 100.00		GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41
+	Hs
		835482 TTC28_HUMAN (6-600): 9.96e-43: 172: 15.81		GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00
+	Hs
		835928 TTC28_HUMAN (6-600): 9.96e-43: 172: 15.81		GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41
+	At
		1105771 HSOP1_ARATH (156-653): 6.93e-33: 137: 12.63		KSG7_ARATH (82-459): 8.13e-154: 444: 59.89
+	At
		1105555 HSOP2_ARATH (3-432): 2.56e-21: 101: 15.01		KSG7_ARATH (82-459): 8.13e-154: 444: 59.89
+	Dm
		576734 Q9VSK6_DROME (1-299): 1.9e-16: 87.1: 18.21		SGG_DROME (68-456): 1.03e-137: 408: 73.15
+	Hs
		684635 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50