HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29121065
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, zf-B_box~zf-C3HC4
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 728
+	Hs
		1252540 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1219888 TRI42_HUMAN (4-402): 2.29e-77: 263: 22.14		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		50950 FSD2_HUMAN (186-661): 6.22e-77: 262: 21.14		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252460 TRI54_HUMAN (1-380): 7.45e-80: 259: 22.80		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1049092 TRI14_HUMAN (152-652): 3.33e-73: 244: 18.90		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252462 TRIM8_HUMAN (4-405): 5.33e-72: 244: 20.10		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Mm
		250640 TRIM9_MOUSE (1-481): 3.96e-71: 248: 23.30		LNX1_MOUSE (1-728): 8.14e-134: 414: 87.98
+	Hs
		536942 TRI27_HUMAN (90-433): 1.46e-30: 128: 14.08		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252493 TRI39_HUMAN (1-396): 3.99e-23: 105: 15.40		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		734704 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1115440 TRI60_HUMAN (3-141): 1.08e-18: 91.3: 19.42		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		585019 RO52_HUMAN (1-295): 2.16e-18: 90.5: 12.70		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1149890 TRI68_HUMAN (108-371): 1.05e-14: 79: 15.39		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1170960 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		1021518 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		280047 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MPDZ_HUMAN (513-728): 2.84e-20: 98.6: 18.43
+	Hs
		1049988 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52