HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: GMCL1 (Q96IK5)
Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29)
Gene: GMCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.50	0.655

Property	Details
Experiments	25416956, 25910212, 32296183, 31515488, unassigned1304
Identification Methods	two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 515
+	Hs
		175688 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		Q53SE7_HUMAN (1-515): 0: 543: 100.00
+	Hs
		1121913 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		Q53SE7_HUMAN (1-515): 0: 543: 100.00
+	Hs
		1294555 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		1121909 TRI54_HUMAN (1-380): 7.45e-80: 259: 22.80		Q53SE7_HUMAN (1-515): 0: 543: 100.00
+	Hs
		1294536 TRI54_HUMAN (1-380): 7.45e-80: 259: 22.80		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		585035 RO52_HUMAN (1-295): 2.16e-18: 90.5: 12.70		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		734698 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		GMCL2_HUMAN (1-513): 0: 538: 90.84
+	Hs
		135027 TRI38_HUMAN (2-249): 1.78e-15: 81.3: 16.94		Q53SE7_HUMAN (1-515): 0: 543: 100.00
+	Hs
		135039 TRI38_HUMAN (2-249): 1.78e-15: 81.3: 16.94		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		242856 TRI13_HUMAN (1-97): 1.22e-14: 78.2: 40.21		Q53SE7_HUMAN (1-515): 0: 543: 100.00
+	Hs
		242880 TRI13_HUMAN (1-97): 1.22e-14: 78.2: 40.21		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		307213 TRIM9_HUMAN (1-659): 6.49e-114: 359: 23.84		KLHL2_HUMAN (16-347): 1.66e-73: 245: 15.02
+	Hs
		1049207 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00
+	Hs
		1049242 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00
+	Hs
		1170733 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		KBTB2_HUMAN (74-290): 7.87e-64: 220: 21.10
+	Hs
		307212 TRIM8_HUMAN (4-405): 5.33e-72: 244: 20.10		KLHL2_HUMAN (16-347): 1.66e-73: 245: 15.02
+	Hs
		1103512 TRI42_HUMAN (4-402): 2.29e-77: 263: 22.14		KLH38_HUMAN (98-309): 1.24e-35: 142: 21.60
+	Hs
		1103540 TRI54_HUMAN (1-380): 7.45e-80: 259: 22.80		KLH38_HUMAN (98-309): 1.24e-35: 142: 21.60
+	Hs
		1103507 TRI69_HUMAN (99-341): 4.28e-17: 86.7: 14.17		KLH38_HUMAN (98-309): 1.24e-35: 142: 21.60