HitPredict

Interactor 1: HMGB3 (O15347)
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)
Gene: HMGB3

Interactor 2: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 304
+	Hs
		175781 HMGB3_HUMAN (13-180): 3.31e-46: 152: 100.00		Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36
+	Hs
		449564 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		HXA10_HUMAN (100-250): 4.39e-37: 138: 33.54
+	Hs
		175757 HMGB3_HUMAN (13-180): 3.31e-46: 152: 100.00		MEOX1_HUMAN (4-270): 1.53e-28: 111: 36.73
+	Hs
		449499 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		HXC6_HUMAN (51-245): 1.04e-28: 111: 25.38
+	Hs
		595592 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		HXA5_HUMAN (99-262): 1.06e-36: 133: 28.57
+	Mm
		446925 Q60I23_MOUSE (3-94): 1.08e-23: 97.4: 27.17		HXA5_MOUSE (99-262): 8.53e-36: 131: 27.51
+	Ce
		447557 EGL13_CAEEL (4-119): 5.59e-24: 99.7: 20.69		MEC3_CAEEL (31-264): 1.53e-33: 126: 18.68
+	Hs
		595639 SOX17_HUMAN (8-101): 1.64e-21: 92.4: 24.47		HXA5_HUMAN (99-262): 1.06e-36: 133: 28.57
+	Dm
		950090 Q9VUD3_DROME (2-87): 7.21e-26: 105: 24.42		UBX_DROME (40-248): 2.12e-30: 120: 24.88
+	Dm
		114548 M9PCZ7_DROME (3-84): 8.82e-25: 102: 24.39		UBX_DROME (40-248): 2.12e-30: 120: 24.88
+	Dm
		115538 M9PFG6_DROME (7-93): 6.34e-25: 102: 24.14		UBX_DROME (40-248): 2.12e-30: 120: 24.88
+	Mm
		793226 SOX8_MOUSE (8-92): 2.68e-19: 86.6: 24.71		HHEX_MOUSE (122-300): 9.91e-37: 134: 23.37
+	Hs
		449556 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		HXD10_HUMAN (155-245): 2.21e-14: 74.3: 49.45
+	Hs
		567820 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		HXB9_HUMAN (21-252): 3.38e-31: 118: 24.57
+	Hs
		818455 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		ALX4_HUMAN (92-303): 8.04e-29: 115: 24.20
+	Mm
		192288 SOX15_MOUSE (7-90): 1.79e-11: 62.8: 28.57		ALX4_MOUSE (43-303): 1.39e-30: 120: 21.27
+	Hs
		225709 SOX15_HUMAN (7-95): 6.65e-12: 64: 29.21		HXB9_HUMAN (21-252): 3.38e-31: 118: 24.57
+	Hs
		817799 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		MNX1_HUMAN (180-253): 1.37e-14: 75.5: 54.05
+	Mm
		981834 SOX8_MOUSE (8-92): 2.68e-19: 86.6: 24.71		HXC4_MOUSE (186-244): 1.32e-13: 71.2: 61.02
+	Hs
		225715 SOX15_HUMAN (7-95): 6.65e-12: 64: 29.21		MNX1_HUMAN (180-253): 1.37e-14: 75.5: 54.05