HitPredict

Interactor 1: HMGB3 (O15347)
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)
Gene: HMGB3

Interactor 2: TFAP4 (Q01664)
Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41)
Gene: TFAP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19505873
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 338
+	Hs
		449679 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		TFAP4_HUMAN (1-338): 5.12e-162: 457: 100.00
+	Hs
		643329 HMGB2_HUMAN (1-184): 1.09e-40: 139: 69.52		TFAP4_HUMAN (1-338): 5.12e-162: 457: 100.00
+	Hs
		817933 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		TFAP4_HUMAN (1-338): 5.12e-162: 457: 100.00
+	Hs
		225728 SOX15_HUMAN (7-95): 6.65e-12: 64: 29.21		TFAP4_HUMAN (1-338): 5.12e-162: 457: 100.00