HitPredict

Interactor 1: SHIP2 (O15357)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)
Gene: INPPL1

Interactor 2: K2C5 (P13647)
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
Gene: KRT5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032880 - regulation of protein localization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1258 Hs			1 590
+	Hs
		176364 SHIP2_HUMAN (1-1258): 0: 968: 100.00		K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10
+	Hs
		176396 SHIP2_HUMAN (1-1258): 0: 968: 100.00		K22E_HUMAN (140-484): 3.01e-174: 509: 71.88
+	Hs
		176466 SHIP2_HUMAN (1-1258): 0: 968: 100.00		K2C73_HUMAN (1-589): 1.2e-95: 304: 51.78
+	Hs
		176338 SHIP2_HUMAN (1-1258): 0: 968: 100.00		K2C6B_HUMAN (2-503): 6.66e-84: 274: 79.08
+	Hs
		176407 SHIP2_HUMAN (1-1258): 0: 968: 100.00		K2C6C_HUMAN (2-503): 1.6e-83: 273: 78.69
+	Hs
		176454 SHIP2_HUMAN (1-1258): 0: 968: 100.00		K2C79_HUMAN (55-497): 2.34e-79: 261: 66.74
+	Hs
		203197 SYNJ1_HUMAN (186-1224): 0: 604: 16.35		K2C8_HUMAN (140-516): 1.46e-162: 474: 69.23