HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30945288
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001701 - in utero embryonic development GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 759
+	Hs
		1038356 HDAC1_HUMAN (3-385): 0: 588: 62.92		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043137 HDAC2_HUMAN (3-422): 0: 580: 58.63		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		177290 HDAC3_HUMAN (1-428): 0: 600: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1038357 HDAC1_HUMAN (3-385): 0: 588: 62.92		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043489 HDAC2_HUMAN (3-422): 0: 580: 58.63		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1038355 HDAC1_HUMAN (3-385): 0: 588: 62.92		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Mm
		140315 HDAC1_MOUSE (3-385): 0: 588: 62.92		CUL3_MOUSE (32-759): 0: 813: 38.36
+	Hs
		1042193 HDAC2_HUMAN (3-422): 0: 580: 58.63		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1043628 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1042740 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041243 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		CUL1_HUMAN (59-759): 0: 745: 30.55