Interactor 1: TMPS2 (O15393)
Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
Gene: TMPRSS2
Interactor 2: A1AT (P01009)
Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)]
Gene: SERPINA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33741941 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | cleavage reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Serpin~Trypsin |
| Common GO terms | GO:0005576 - extracellular region GO:0070062 - extracellular exosome |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
