HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	19167051, 17932509
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 859
+	Hs
		178290 IPO8_HUMAN (1-1037): 0: 846: 100.00		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		178273 IPO8_HUMAN (1-1037): 0: 846: 100.00		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		178277 IPO8_HUMAN (1-1037): 0: 846: 100.00		AGO4_HUMAN (16-859): 0: 1145: 78.51
+	Hs
		1299142 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		1299143 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		AGO1_HUMAN (17-859): 0: 1182: 83.16