HitPredict

Interactor 1: MRP5 (O15440)
ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11)
Gene: ABCC5

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010008 - endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1437 Hs			1 258
+	Hs
		179391 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		179400 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		179408 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		179406 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		179403 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		179393 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		179401 MRP5_HUMAN (1-1437): 0: 1065: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		179395 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		179422 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26
+	Hs
		437198 MDR1_HUMAN (4-784): 1.33e-110: 382: 12.36		RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00
+	Hs
		437187 MDR1_HUMAN (4-784): 1.33e-110: 382: 12.36		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		437178 MDR1_HUMAN (4-784): 1.33e-110: 382: 12.36		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		436176 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		706692 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		706702 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		706699 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		706695 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545225 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		706693 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		564426 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40