HitPredict

Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 609
+	Hs
		523937 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		XRCC6_HUMAN (1-609): 0: 666: 100.00
+	Hs
		523903 TITIN_HUMAN (60-509): 8.33e-09: 60.8: 10.21		XRCC6_HUMAN (1-609): 0: 666: 100.00
+	Hs
		523752 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		XRCC6_HUMAN (1-609): 0: 666: 100.00
+	Hs
		524926 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77