HitPredict

Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 801
+	Hs
		179644 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		631425 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		179484 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		1067006 NIPBL_HUMAN (160-509): 1.23e-45: 174: 14.00		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		244571 NIPBL_HUMAN (160-509): 1.23e-45: 174: 14.00		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		1067096 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		1056838 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		244791 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		244438 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		179705 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33
+	Hs
		179546 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		TAF1_HUMAN (64-263): 1.16e-16: 87.2: 16.00
+	Hs
		179745 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		PHIP_HUMAN (76-730): 1.12e-13: 77.6: 11.21
+	Hs
		998710 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72