HitPredict

Interactor 1: MUSK (O15146)
Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)
Gene: MUSK

Interactor 2: LRRC1 (Q9BTT6)
Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)
Gene: LRRC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	20463225
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	I-set~LRR_8, Ig_3~LRR_8, LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 869 Hs			1 524
+	Hs
		179629 MUSK_HUMAN (1-869): 0: 786: 100.00		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		179609 MUSK_HUMAN (1-869): 0: 786: 100.00		SCRIB_HUMAN (209-522): 2.89e-45: 173: 21.45
+	At
		87903 Y5182_ARATH (203-865): 1.6e-142: 446: 16.69		RGI3_ARATH (3-465): 7.61e-69: 241: 24.95
+	Hs
		720306 UFO_HUMAN (2-868): 2.36e-152: 471: 20.71		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		720218 UFO_HUMAN (2-868): 2.36e-152: 471: 20.71		SCRIB_HUMAN (209-522): 2.89e-45: 173: 21.45
+	Hs
		777769 VGFR3_HUMAN (2-861): 7.01e-173: 538: 22.36		LRC40_HUMAN (13-351): 4.58e-17: 86.3: 23.78
+	At
		1192452 SERK1_ARATH (311-869): 3.13e-141: 434: 17.43		ERECT_ARATH (3-333): 1.43e-44: 170: 23.24
+	At
		1490268 SERK2_ARATH (322-869): 2.18e-140: 432: 17.59		BRL2_ARATH (83-440): 8.66e-42: 162: 22.87
+	At
		87925 Y5182_ARATH (203-865): 1.6e-142: 446: 16.69		PXC2_ARATH (5-262): 7.08e-37: 147: 24.76
+	At
		88680 BAK1_ARATH (290-868): 2.81e-140: 431: 17.72		GSO1_ARATH (134-522): 1.15e-40: 159: 19.50
+	At
		1443982 SERK2_ARATH (322-869): 2.18e-140: 432: 17.59		PXC2_ARATH (5-262): 7.08e-37: 147: 24.76
+	At
		1250985 SERK1_ARATH (311-869): 3.13e-141: 434: 17.43		ERL2_ARATH (3-298): 1.07e-35: 144: 20.00
+	Hs
		720327 UFO_HUMAN (2-868): 2.36e-152: 471: 20.71		LRC40_HUMAN (13-351): 4.58e-17: 86.3: 23.78
+	At
		87930 Y5182_ARATH (203-865): 1.6e-142: 446: 16.69		CLV1_ARATH (14-176): 1.27e-24: 110: 25.15
+	At
		308162 SERK2_ARATH (322-869): 2.18e-140: 432: 17.59		SKM1_ARATH (298-522): 4.37e-23: 105: 12.20
+	At
		87908 Y5182_ARATH (203-865): 1.6e-142: 446: 16.69		BAME1_ARATH (366-521): 5.63e-15: 80: 9.88
+	At
		1427617 SERK2_ARATH (322-869): 2.18e-140: 432: 17.59		PEPR2_ARATH (379-523): 5.02e-18: 90: 12.93
+	At
		235856 SERK2_ARATH (322-869): 2.18e-140: 432: 17.59		BAME1_ARATH (366-521): 5.63e-15: 80: 9.88
+	At
		87905 Y5182_ARATH (203-865): 1.6e-142: 446: 16.69		Y4361_ARATH (143-390): 2.64e-10: 65.5: 33.33
+	At
		88963 SERK2_ARATH (322-869): 2.18e-140: 432: 17.59		Y4361_ARATH (143-390): 2.64e-10: 65.5: 33.33