HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, Ig_3~LRR_8, LRR_8~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 1655
+	Hs
		1122235 EPHA7_HUMAN (2-833): 0: 626: 19.48		SCRIB_HUMAN (1-1655): 0: 940: 100.00
+	Hs
		710831 EPHB2_HUMAN (2-821): 0: 618: 19.70		SCRIB_HUMAN (1-1655): 0: 940: 100.00
+	Hs
		710238 EPHA2_HUMAN (1-843): 0: 616: 19.51		SCRIB_HUMAN (1-1655): 0: 940: 100.00
+	Hs
		472058 MET_HUMAN (536-799): 3.43e-66: 243: 45.90		SCRIB_HUMAN (1-1655): 0: 940: 100.00
+	Hs
		720327 UFO_HUMAN (1-894): 0: 782: 100.00		LRC40_HUMAN (13-349): 4.24e-21: 101: 25.80
+	Hs
		720208 UFO_HUMAN (1-894): 0: 782: 100.00		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		720306 UFO_HUMAN (1-894): 0: 782: 100.00		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		710453 EPHA2_HUMAN (1-843): 0: 616: 19.51		LRRC1_HUMAN (1-189): 8.84e-41: 161: 27.51
+	Hs
		932062 EPHA4_HUMAN (2-836): 0: 645: 19.10		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		710651 EPHA3_HUMAN (2-810): 0: 656: 19.95		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		640276 EPHA1_HUMAN (1-843): 0: 561: 20.38		LRRC1_HUMAN (1-189): 8.84e-41: 161: 27.51
+	Hs
		710408 EPHA2_HUMAN (1-843): 0: 616: 19.51		DLG3_HUMAN (724-947): 1.79e-19: 97.4: 31.23
+	Hs
		932119 EPHA4_HUMAN (2-836): 0: 645: 19.10		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		1091501 EPHA7_HUMAN (2-833): 0: 626: 19.48		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		931842 EPHA5_HUMAN (2-812): 0: 625: 20.50		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		710208 EPHA2_HUMAN (1-843): 0: 616: 19.51		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		1147411 EPHA7_HUMAN (2-833): 0: 626: 19.48		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		931882 EPHA5_HUMAN (2-812): 0: 625: 20.50		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		710440 EPHA2_HUMAN (1-843): 0: 616: 19.51		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		641241 FGFR2_HUMAN (17-859): 1.11e-164: 502: 21.57		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27