Interactor 1: INSI1 (O15503)
Insulin-induced gene 1 protein (INSIG-1)
Gene: INSIG1

Interactor 2: SCAP (Q12770)
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)
Gene: SCAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 26555173, 32111832, 32322062, 32432943, 12842885, 30563842, 33961781, 18835813, 17043353, 12242332, 23564452
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains INSIG~Sterol-sensing
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0032933 - SREBP signaling pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 277
Hs

1 1279
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024