HitPredict

Interactor 1: ARPC5 (O15511)
Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)
Gene: ARPC5

Interactor 2: ARP3B (Q9P1U1)
Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4)
Gene: ACTR3B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	28514442, 33961781, 17353931, 29568061, 24981860
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~P16-Arc
Common GO terms	GO:0005737 - cytoplasm GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 151 Hs			1 418
+	Hs
		181310 ARPC5_HUMAN (1-151): 2.22e-73: 218: 100.00		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Hs
		1308638 ARP5L_HUMAN (1-151): 8.15e-65: 196: 68.18		ARP3B_HUMAN (1-418): 0: 590: 100.00
+	Hs
		896810 ARP5L_HUMAN (1-151): 8.15e-65: 196: 68.18		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Dm
		689669 Q9VQD8_DROME (1-147): 1.96e-64: 195: 52.70		ARP3_DROME (1-418): 0: 557: 79.67
+	Hs
		181314 ARPC5_HUMAN (1-151): 2.22e-73: 218: 100.00		ACTG_HUMAN (1-414): 0: 528: 35.18
+	Hs
		891995 ARP5L_HUMAN (1-151): 8.15e-65: 196: 68.18		ACTB_HUMAN (1-414): 0: 528: 35.42
+	Hs
		929987 ARP5L_HUMAN (1-151): 8.15e-65: 196: 68.18		ACTG_HUMAN (1-414): 0: 528: 35.18
+	Sc
		775027 ARPC5_YEAST (9-151): 2.97e-51: 162: 25.49		ARP3_YEAST (6-417): 2.6e-173: 493: 57.46