HitPredict

Interactor 1: RPB4 (O15514)
DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16)
Gene: POLR2D

Interactor 2: RPB9 (P36954)
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)
Gene: POLR2I

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	24981860, 35271311, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 125
+	Hs
		181484 RPB4_HUMAN (1-142): 4e-59: 181: 100.00		RPC10_HUMAN (14-125): 6.76e-35: 117: 26.79
+	Hs
		181476 RPB4_HUMAN (1-142): 4e-59: 181: 100.00		RPA12_HUMAN (12-125): 2.72e-23: 89: 16.67
+	Sc
		593042 RPB4_YEAST (42-140): 3.4e-27: 102: 35.58		RPB9_YEAST (11-124): 3.78e-38: 126: 43.86
+	Sc
		425452 RPB4_YEAST (42-140): 3.4e-27: 102: 35.58		TFS2_YEAST (41-124): 2.88e-19: 82.5: 17.86