HitPredict

Interactor 1: RPB4 (O15514)
DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16)
Gene: POLR2D

Interactor 2: RPR1A (Q96P16)
Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)
Gene: RPRD1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 312
+	Hs
		181463 RPB4_HUMAN (1-142): 4e-59: 181: 100.00		RPR1B_HUMAN (1-312): 6.18e-86: 262: 65.34
+	Hs
		181423 RPB4_HUMAN (1-142): 4e-59: 181: 100.00		RPRD2_HUMAN (9-308): 1.26e-69: 236: 26.84
+	Hs
		181372 RPB4_HUMAN (1-142): 4e-59: 181: 100.00		SCAF4_HUMAN (8-271): 4.99e-45: 165: 17.88
+	Sc
		593088 RPB4_YEAST (42-140): 3.4e-27: 102: 35.58		RT103_YEAST (4-304): 1.57e-44: 158: 19.74
+	Sp
		252117 RPB4_SCHPO (14-141): 4.49e-46: 147: 41.09		SEB1_SCHPO (1-309): 3.96e-13: 71.5: 11.30