Protein: LIN54
Protein lin-54 homolog (CXC domain-containing protein 1)

Gene: LIN54
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q6MZP7

Gene Ontology (top 5):
GO:0001067 - transcription regulatory region nucleic acid binding
GO:0003680 - minor groove of adenine-thymine-rich DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

997769

RBBP4
Histone-binding protein RBBP4

5

4

Small-scale

0.722

High

1154417

LIN37
Protein lin-37 homolog

5

3

Small-scale

0.718

High

1137025

LIN9
Protein lin-9 homolog

4

4

Small-scale

0.699

High

486924

MYBB
Myb-related protein B

4

4

Small-scale

0.691

High

486858

MYBA
Myb-related protein A

3

4

Small-scale

0.675

High

1154415

LMBL2
Lethal(3)malignant brain tumor-like protein 2

3

2

High-throughput

0.675

High

997129

RBL2
Retinoblastoma-like protein 2

3

5

Small-scale

0.667

High

1119816

LIN52
Protein lin-52 homolog

3

1

Small-scale

0.667

High

572996

PRS6A
26S proteasome regulatory subunit 6A

3

0

High-throughput

0.638

High

1039087

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

1

High-throughput

0.628

High

1050559

TFDP2
Transcription factor Dp-2

2

2

Small-scale

0.628

High

1047499

NFYC
Nuclear transcription factor Y subunit gamma

3

0

High-throughput

0.625

High

1081290

E2F4
Transcription factor E2F4

2

3

Small-scale

0.611

High

735062

ZNF76
Zinc finger protein 76

2

1

High-throughput

0.606

High

856023

ZN143
Zinc finger protein 143

2

1

High-throughput

0.606

High

970924

SP3
Transcription factor Sp3

2

3

High-throughput

0.606

High

1154427

IKZF5
Zinc finger protein Pegasus

2

0

High-throughput

0.602

High

818156

SOX2
Transcription factor SOX-2

2

2

Small-scale

0.584

High

884185

KLF3
Krueppel-like factor 3

2

4

High-throughput

0.584

High

1073675

SF3A2
Splicing factor 3A subunit 2

2

0

High-throughput

0.580

High

1154412

BANP
Protein BANP

2

0

High-throughput

0.580

High

347058

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

917445

H4
Histone H4

2

0

Small-scale

0.547

High

993324

FOXM1
Forkhead box protein M1

1

1

High-throughput

0.536

High

1050510

TFDP1
Transcription factor Dp-1

1

2

Small-scale

0.536

High

1154433

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

1

High-throughput

0.536

High

1029256

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1154429

FOXJ2
Forkhead box protein J2

1

0

High-throughput

0.513

High

414320

RB
Retinoblastoma-associated protein

1

5

Small-scale

0.501

High

316916

KLF8
Krueppel-like factor 8

1

5

High-throughput

0.479

High

487523

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

552959

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

632776

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.479

High

660149

RBL1
Retinoblastoma-like protein 1

1

5

Small-scale

0.479

High

692150

ELF1
ETS-related transcription factor Elf-1

1

4

High-throughput

0.479

High

727538

HNF1B
Hepatocyte nuclear factor 1-beta

1

1

High-throughput

0.479

High

727759

SOX5
Transcription factor SOX-5

1

2

High-throughput

0.479

High

785371

ELK3
ETS domain-containing protein Elk-3

1

4

High-throughput

0.479

High

824109

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

934882

H31
Histone H3.1

1

1

High-throughput

0.479

High

952408

H33
Histone H3.3

1

1

High-throughput

0.479

High

1026445

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1077559

ELF2
ETS-related transcription factor Elf-2

1

3

High-throughput

0.479

High

1154413

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.479

High

1154414

SP7
Transcription factor Sp7

1

5

High-throughput

0.479

High

1154418

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

1154420

FEV
Protein FEV

1

4

High-throughput

0.479

High

1154421

ELF4
ETS-related transcription factor Elf-4

1

4

High-throughput

0.479

High

1154423

KLF16
Krueppel-like factor 16

1

4

High-throughput

0.479

High

1154431

KLF15
Krueppel-like factor 15

1

5

High-throughput

0.479

High

1154435

KLF12
Krueppel-like factor 12

1

4

High-throughput

0.479

High

179685

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

227776

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

386927

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

641446

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.458

High

651463

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

668759

PML
Protein PML

1

0

High-throughput

0.458

High

679120

TLX1
T-cell leukemia homeobox protein 1

1

0

High-throughput

0.458

High

720705

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

782572

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

High-throughput

0.458

High

831422

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

839765

LHX2
LIM/homeobox protein Lhx2

1

0

High-throughput

0.458

High

918443

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1027055

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1060306

NFIX
Nuclear factor 1 X-type

1

0

High-throughput

0.458

High

1154410

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1154411

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1154422

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

1154425

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1154428

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1154430

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.458

High

1154434

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

177321

HDAC3
Histone deacetylase 3

1

1

Small-scale

0.445

High

261531

NCOR1
Nuclear receptor corepressor 1

1

1

Small-scale

0.445

High

1071523

E2F5
Transcription factor E2F5

1

3

Small-scale

0.445

High

1002043

ARL16
ADP-ribosylation factor-like protein 16

1

1

High-throughput

0.437

High

267292

HSBP1
Heat shock factor-binding protein 1

1

0

Small-scale

0.426

High

376096

CYTB
Cystatin-B

1

0

Small-scale

0.426

High

418363

NPM
Nucleophosmin

1

0

Small-scale

0.426

High

609916

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

Small-scale

0.426

High

670839

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

Small-scale

0.426

High

1034590

GOGA4
Golgin subfamily A member 4

1

0

Small-scale

0.426

High

1154419

PARK7
Parkinson disease protein 7

1

0

Small-scale

0.426

High

1154424

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

0

Small-scale

0.426

High

1154432

NSF1C
NSFL1 cofactor p47

1

0

Small-scale

0.426

High

199912

SPIT2
Kunitz-type protease inhibitor 2

3

0

High-throughput

0.347

High

390956

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.328

High

1035084

TUSC3
Tumor suppressor candidate 3

2

0

High-throughput

0.328

High

179199

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

473133

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

515880

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

763015

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

1154416

CC74A
Coiled-coil domain-containing protein 74A

1

0

High-throughput

0.279

Low

1154426

GSTO2
Glutathione S-transferase omega-2

1

0

High-throughput

0.279

Low

352641

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

928617

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

392690

B3A2
Anion exchange protein 2

1

0

Small-scale

0.232

Low

400578

RLA2
Large ribosomal subunit protein P2

1

0

Small-scale

0.232

Low

828791

SRP09
Signal recognition particle 9 kDa protein

1

0

Small-scale

0.232

Low

901884

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

0

Small-scale

0.232

Low

1034656

HAP28
28 kDa heat- and acid-stable phosphoprotein

1

0

Small-scale

0.232

Low

1066092

IF4H
Eukaryotic translation initiation factor 4H

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024