Interactor 1: CLOCK (O15516)
Circadian locomoter output cycles protein kaput (hCLOCK) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 8) (bHLHe8)
Gene: CLOCK

Interactor 2: CRY1 (Q16526)
Cryptochrome-1
Gene: CRY1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.629

The method score is based on:

Property Details
Experiments 23555304, 28388406, 32538895
Identification Methods two hybrid, anti bait coimmunoprecipitation, pull down
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0007623 - circadian rhythm
GO:0032922 - circadian regulation of gene expression
GO:0042752 - regulation of circadian rhythm
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 846
Hs

1 586
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Last updated: 15 Jul 2024