HitPredict

Interactor 1: TPSN (O15533)
Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)
Gene: TAPBP

Interactor 2: CALR (P27797)
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)
Gene: CALR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

The method score is based on:

Property	Details
Experiments	30021884, 11823531, 8769474
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002502 - peptide antigen assembly with MHC class I protein complex GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0030670 - phagocytic vesicle membrane GO:0033116 - endoplasmic reticulum-Golgi intermediate compartment membrane and 4 others more... GO:0042824 - MHC class I peptide loading complex GO:0044183 - protein folding chaperone GO:0051082 - unfolded protein binding GO:0098553 - lumenal side of endoplasmic reticulum membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	448
Hs

1	417

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024