HitPredict

Interactor 1: O18302 (O18302)
PDZ domain-containing protein
Gene: gopc-1

Interactor 2: SIAH1 (Q965X6)
E3 ubiquitin-protein ligase siah-1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1)
Gene: siah-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	0.50	0.451

Property	Details
Experiments	14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 414 Ce			1 419
+	Ce
		185387 O18301_CAEEL (76-380): 3.25e-47: 166: 18.45		SIAH1_CAEEL (1-419): 1.48e-154: 445: 100.00
+	Hs
		1204896 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		TRI50_HUMAN (148-419): 2.15e-52: 184: 15.03
+	Hs
		1232922 LNX2_HUMAN (89-400): 3.6e-30: 124: 13.19		PZRN3_HUMAN (140-265): 5.13e-30: 124: 23.88
+	Hs
		129581 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		TRAF5_HUMAN (140-322): 1.46e-36: 142: 14.98
+	Hs
		1149890 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		TRI68_HUMAN (142-357): 1.15e-36: 141: 17.89
+	Hs
		1168357 LNX2_HUMAN (89-400): 3.6e-30: 124: 13.19		PZRN4_HUMAN (140-242): 3e-17: 86: 22.73
+	Hs
		1252445 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		TRAF4_HUMAN (139-303): 6.84e-32: 128: 17.74
+	Hs
		1252569 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		TRAF6_HUMAN (91-318): 7.15e-31: 125: 13.50
+	Hs
		1252551 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		PZRN3_HUMAN (140-265): 5.13e-30: 124: 23.88
+	Hs
		942403 DLG4_HUMAN (1-307): 1.76e-13: 74.3: 8.62		TRAF6_HUMAN (91-318): 7.15e-31: 125: 13.50
+	Hs
		1168358 LNX1_HUMAN (124-398): 8.67e-16: 81.5: 18.21		PZRN4_HUMAN (140-242): 3e-17: 86: 22.73