Protein: ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic (EC 1.2.1.-) (EC 1.2.1.4) (Mg(2+)-activated acetaldehyde dehydrogenase) (Mg(2+)-ACDH)

Gene: ALDH6, ALD6
Organism: Saccharomyces cerevisiae S288C
Interactions: 175
UniProt ID: P54115

Gene Ontology (top 5):
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0004030 - aldehyde dehydrogenase [NAD(P)+] activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006068 - ethanol catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797516

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

5

High-throughput

0.640

High

680917

HS104
Heat shock protein 104

3

3

Small-scale

0.633

High

494683

HSP72
Heat shock protein SSA2

3

9

High-throughput

0.624

High

743429

UGA2
Succinate-semialdehyde dehydrogenase [NADP(+)]

1

13

High-throughput

0.618

High

774656

LYS12
Homoisocitrate dehydrogenase, mitochondrial

2

3

High-throughput

0.611

High

628344

SIS1
Protein SIS1

2

4

High-throughput

0.601

High

343668

PMG1
Phosphoglycerate mutase 1

2

0

High-throughput

0.585

High

867509

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

13

Small-scale

0.575

High

492097

HSP71
Heat shock protein SSA1

2

9

High-throughput

0.571

High

512321

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.571

High

633468

MAS5
Mitochondrial protein import protein MAS5

2

1

High-throughput

0.571

High

368303

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.536

High

498570

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.536

High

657095

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

3

High-throughput

0.536

High

687453

EF2
Elongation factor 2

1

1

High-throughput

0.536

High

867511

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

524407

CAF20
Cap-associated protein CAF20

2

2

High-throughput

0.533

High

691097

HOG1
Mitogen-activated protein kinase HOG1

2

2

High-throughput

0.533

High

485798

IF4A
ATP-dependent RNA helicase eIF4A

2

1

High-throughput

0.521

High

693818

CBS
Cystathionine beta-synthase

1

3

High-throughput

0.515

High

540135

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.513

High

864577

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

867533

NEW1
[NU+] prion formation protein 1

1

0

High-throughput

0.513

High

350908

YPT1
GTP-binding protein YPT1

1

1

High-throughput

0.500

High

614767

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.500

High

772260

RFC4
Replication factor C subunit 4

1

2

High-throughput

0.500

High

860036

RPN14
26S proteasome regulatory subunit RPN14

1

4

High-throughput

0.500

High

867539

SMC6
Structural maintenance of chromosomes protein 6

1

3

High-throughput

0.500

High

664520

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.480

High

690333

CDC11
Cell division control protein 11

1

0

High-throughput

0.479

High

748222

CS111
F-box protein COS111

1

0

High-throughput

0.479

High

748374

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.479

High

756852

RIX1
Pre-rRNA-processing protein RIX1

1

0

High-throughput

0.479

High

764111

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.479

High

772502

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.479

High

774236

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.479

High

863689

PAP2
Poly(A) RNA polymerase protein 2

1

0

High-throughput

0.479

High

867513

IMA1
Importin subunit alpha

1

0

High-throughput

0.479

High

867516

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.479

High

366716

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

383288

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

405765

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

407236

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

411059

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.479

High

413652

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

419935

SNF1
Carbon catabolite-derepressing protein kinase

1

1

Small-scale

0.479

High

425644

KAPR
cAMP-dependent protein kinase regulatory subunit

1

2

Small-scale

0.479

High

439525

FUMH
Fumarate hydratase, mitochondrial

1

1

High-throughput

0.479

High

472336

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

520633

YPK1
Serine/threonine-protein kinase YPK1

1

1

High-throughput

0.479

High

544225

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

580868

ARF2
ADP-ribosylation factor 2

1

1

High-throughput

0.479

High

583248

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.479

High

605116

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.479

High

605379

HSP74
Heat shock protein SSA4

1

9

High-throughput

0.479

High

701029

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

737193

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

752599

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

762455

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

772728

MPM1
Mitochondrial peculiar membrane protein 1

1

1

High-throughput

0.479

High

860560

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

863032

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

866776

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.479

High

342989

ENO2
Enolase 2

1

0

High-throughput

0.458

High

343419

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

358201

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

389318

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

408055

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

471192

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

521029

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

632023

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

645587

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

657266

URA7
CTP synthase 1

1

0

High-throughput

0.458

High

657798

MGLL
Monoglyceride lipase

1

0

High-throughput

0.458

High

700563

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

706423

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

730059

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

747290

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

756998

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

774992

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

777131

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

812653

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

867512

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

867525

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

867531

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

867537

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.458

High

429746

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

2

High-throughput

0.457

High

586430

PRP6
Pre-mRNA-splicing factor 6

1

4

High-throughput

0.457

High

593366

CG11
G1/S-specific cyclin CLN1

1

4

High-throughput

0.457

High

594354

PP11
Serine/threonine-protein phosphatase PP1-1

1

1

High-throughput

0.457

High

644767

RFA2
Replication factor A protein 2

1

3

High-throughput

0.457

High

678751

RAD16
DNA repair protein RAD16

1

1

High-throughput

0.457

High

697306

RAD24
Checkpoint protein RAD24

1

3

High-throughput

0.457

High

699410

RAD54
DNA repair and recombination protein RAD54

1

4

High-throughput

0.457

High

763820

RBG1
Ribosome-interacting GTPase 1

1

3

High-throughput

0.457

High

765951

HAT2
Histone acetyltransferase type B subunit 2

1

6

High-throughput

0.457

High

772430

RFC2
Replication factor C subunit 2

1

2

High-throughput

0.457

High

772483

RAD26
DNA repair and recombination protein RAD26

1

4

High-throughput

0.457

High

784405

COPB2
Coatomer subunit beta'

1

3

High-throughput

0.457

High

861251

RBG2
Ribosome-interacting GTPase 2

1

3

High-throughput

0.457

High

867510

CDC14
Tyrosine-protein phosphatase CDC14

1

3

High-throughput

0.457

High

867522

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.457

High

867523

KU80
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.457

High

867524

SEN15
tRNA-splicing endonuclease subunit SEN15

1

1

High-throughput

0.457

High

867528

RBX1
RING-box protein HRT1

1

1

High-throughput

0.457

High

867535

RAD59
DNA repair protein RAD59

1

1

High-throughput

0.457

High

424656

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.445

High

695281

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

769152

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

773722

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

775641

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.445

High

634259

GID7
Glucose-induced degradation protein 7

1

2

High-throughput

0.437

High

663011

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

703707

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.437

High

705900

IXR1
Intrastrand cross-link recognition protein

1

2

Small-scale

0.437

High

753906

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.437

High

762003

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.437

High

812070

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

858900

VID30
Vacuolar import and degradation protein 30

1

1

High-throughput

0.437

High

858998

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.437

High

860070

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

1

1

High-throughput

0.437

High

864131

HST2
NAD-dependent protein deacetylase HST2

1

7

High-throughput

0.437

High

867519

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.437

High

867527

SUB2
ATP-dependent RNA helicase SUB2

1

2

High-throughput

0.437

High

867532

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

867534

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

867538

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.437

High

592959

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

360988

TBB
Tubulin beta chain

1

3

High-throughput

0.407

High

454648

TBA3
Tubulin alpha-3 chain

1

5

High-throughput

0.407

High

785156

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.407

High

810099

PFD1
Prefoldin subunit 1

1

2

High-throughput

0.407

High

810395

JJJ2
J protein JJJ2

1

2

High-throughput

0.407

High

867517

CLU
Clustered mitochondria protein 1

1

3

High-throughput

0.407

High

867518

WDR59
Maintenance of telomere capping protein 5

1

9

High-throughput

0.407

High

644816

RFA3
Replication factor A protein 3

2

0

High-throughput

0.310

High

775224

ULP2
Ubiquitin-like-specific protease 2

2

0

Small-scale

0.306

High

565284

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.279

Low

733895

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

765757

PP2C2
Protein phosphatase 2C homolog 2

1

0

High-throughput

0.279

Low

774571

FYV10
Protein FYV10

1

0

High-throughput

0.269

Low

419565

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.261

Low

604306

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.261

Low

657755

YJU2
Splicing factor YJU2

1

0

High-throughput

0.261

Low

696381

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.261

Low

746160

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.261

Low

753165

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.261

Low

791221

SKP2
F-box protein SKP2

1

0

High-throughput

0.261

Low

811850

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.261

Low

859712

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.261

Low

867520

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.261

Low

867530

DIA2
Protein DIA2

1

0

High-throughput

0.261

Low

867536

WTM1
Transcriptional modulator WTM1

1

0

High-throughput

0.261

Low

572815

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

619500

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

633884

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

692052

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

746559

POA1
ADP-ribose 1''-phosphate phosphatase

1

0

High-throughput

0.249

Low

749078

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

751133

RCK2
Serine/threonine-protein kinase RCK2

1

0

High-throughput

0.249

Low

753364

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

755613

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.249

Low

783295

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.249

Low

811423

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.249

Low

814709

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.249

Low

837519

LGUL
Glyoxalase I

1

0

High-throughput

0.249

Low

866096

NRK1
Nicotinamide riboside kinase

1

0

High-throughput

0.249

Low

867514

COFI
Cofilin

1

0

High-throughput

0.249

Low

867515

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.249

Low

867521

YD391
Uncharacterized protein YDR391C

1

0

High-throughput

0.249

Low

867526

YL352
F-box protein YLR352W

1

0

High-throughput

0.249

Low

867529

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

399587

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

760665

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024