HitPredict

Interactor 1: STX7 (O15400)
Syntaxin-7
Gene: STX7

Interactor 2: GOSR1 (O95249)
Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)
Gene: GOSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0005484 - SNAP receptor activity GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 250
+	Hs
		96841 STX7_HUMAN (1-261): 9.29e-70: 217: 100.00		E9PCW1_HUMAN (1-250): 5.31e-111: 320: 99.20
+	Hs
		331890 STX12_HUMAN (10-244): 3.43e-58: 188: 54.01		GOSR1_HUMAN (1-250): 6.43e-114: 328: 100.00
+	Hs
		96852 STX12_HUMAN (10-244): 3.43e-58: 188: 54.01		E9PCW1_HUMAN (1-250): 5.31e-111: 320: 99.20
+	Hs
		331862 STX3_HUMAN (4-237): 2.82e-52: 173: 23.33		GOSR1_HUMAN (1-250): 6.43e-114: 328: 100.00
+	Hs
		96848 STX3_HUMAN (4-237): 2.82e-52: 173: 23.33		E9PCW1_HUMAN (1-250): 5.31e-111: 320: 99.20
+	Dm
		1174536 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		GOSR1_DROME (5-250): 8.44e-72: 221: 45.75
+	Dm
		1264433 Q7K0X9_DROME (10-256): 4.52e-44: 152: 38.85		GOSR1_DROME (5-250): 8.44e-72: 221: 45.75
+	Dm
		1472276 Q9VU45_DROME (10-260): 1.86e-43: 150: 23.41		GOSR1_DROME (5-250): 8.44e-72: 221: 45.75
+	Dm
		1472273 Q9VR90_DROME (149-246): 5.7e-13: 69.7: 41.84		GOSR1_DROME (5-250): 8.44e-72: 221: 45.75
+	Sc
		746131 PEP12_YEAST (62-236): 5.47e-11: 63.2: 25.68		GOSR1_YEAST (36-246): 6.43e-56: 180: 24.06