HitPredict

Interactor 1: CLD4 (O35054)
Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor)
Gene: Cldn4

Interactor 2: ZO1 (P39447)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: Tjp1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10601346
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0016020 - membrane GO:0016324 - apical plasma membrane GO:0016327 - apicolateral plasma membrane and 1 others more... GO:0070160 - tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Mm			1 1745
+	Mm
		291871 CLD1_MOUSE (1-210): 3.43e-87: 257: 44.55		ZO1_MOUSE (1-1745): 0: 993: 100.00
+	Hs
		315115 CLD7_HUMAN (1-210): 1.38e-88: 261: 47.39		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Mm
		761870 CLD7_MOUSE (1-210): 2.16e-84: 250: 50.24		ZO1_MOUSE (1-1745): 0: 993: 100.00
+	Mm
		761869 CLD8_MOUSE (1-199): 3.36e-81: 242: 45.05		ZO1_MOUSE (1-1745): 0: 993: 100.00
+	Hs
		881971 CLD8_HUMAN (1-199): 6.24e-82: 244: 46.54		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Hs
		325492 CLD1_HUMAN (1-210): 9.42e-82: 243: 46.92		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Hs
		881967 CLD6_HUMAN (1-206): 8.61e-80: 239: 61.65		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Mm
		222686 CLD5_MOUSE (1-206): 1.92e-77: 233: 50.24		ZO1_MOUSE (1-1745): 0: 993: 100.00
+	Hs
		131310 CLD5_HUMAN (1-207): 3.17e-78: 235: 49.05		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Mm
		761868 CLD3_MOUSE (3-203): 2.01e-76: 230: 69.65		ZO1_MOUSE (1-1745): 0: 993: 100.00
+	Hs
		146030 CLD4_HUMAN (1-210): 1.54e-77: 232: 83.33		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Hs
		183195 CLD3_HUMAN (3-204): 9.47e-77: 231: 67.00		ZO1_HUMAN (1-1745): 0: 989: 90.79
+	Mm
		291873 CLD1_MOUSE (1-210): 3.43e-87: 257: 44.55		ZO3_MOUSE (13-925): 3.01e-132: 438: 38.42
+	Hs
		303739 CLD1_HUMAN (1-210): 9.42e-82: 243: 46.92		ZO3_HUMAN (13-927): 7.42e-137: 451: 39.28
+	Mm
		192031 CLD4_MOUSE (1-210): 6.3e-88: 259: 100.00		MPDZ_MOUSE (6-329): 4.5e-23: 109: 17.13
+	Mm
		291872 CLD1_MOUSE (1-210): 3.43e-87: 257: 44.55		MPDZ_MOUSE (6-329): 4.5e-23: 109: 17.13
+	Hs
		325501 CLD1_HUMAN (1-210): 9.42e-82: 243: 46.92		ZO2_HUMAN (170-518): 1.13e-18: 95.4: 14.47
+	Hs
		325496 CLD1_HUMAN (1-210): 9.42e-82: 243: 46.92		INADL_HUMAN (51-506): 3.52e-15: 84.1: 14.56
+	Mm
		291874 CLD1_MOUSE (1-210): 3.43e-87: 257: 44.55		ZO2_MOUSE (413-562): 4.65e-09: 63.8: 21.52
+	Hs
		146034 CLD4_HUMAN (1-210): 1.54e-77: 232: 83.33		DLG1_HUMAN (264-512): 3.5e-15: 83.4: 15.95