HitPredict

Interactor 1: DAXX (O35613)
Death domain-associated protein 6 (Daxx)
Gene: DAXX

Interactor 2: MDM2 (P23804)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 18566590, 15364927
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 739
Mm

1 489
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024