HitPredict

Interactor 1: AFAD (O35889)
Afadin (Afadin adherens junction formation factor) (Protein Af-6)
Gene: Afdn

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030424 - axon GO:0036477 - somatodendritic compartment
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1829 Rn			1 752
+	Rn
		94105 AFAD_RAT (1-1829): 0: 1129: 100.00		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		496652 AFAD_HUMAN (1-1829): 0: 1121: 92.63		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		876522 AFAD_HUMAN (1-1829): 0: 1121: 92.63		DAPLE_HUMAN (3-620): 7.14e-32: 135: 10.16
+	Hs
		297818 AFAD_HUMAN (1-1829): 0: 1121: 92.63		K0754_HUMAN (290-748): 3.93e-19: 95.1: 10.46
+	Hs
		496927 KIF1A_HUMAN (40-608): 1.5e-98: 354: 14.91		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		216897 KIF1C_HUMAN (40-618): 1.21e-80: 292: 14.92		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Ce
		109403 UN104_CAEEL (31-625): 9.84e-106: 376: 16.80		H2KY94_CAEEL (443-682): 7.74e-21: 94.5: 28.52
+	Hs
		1056837 KIF14_HUMAN (41-700): 5.53e-81: 298: 14.33		MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08
+	Hs
		1066964 KIF14_HUMAN (41-700): 5.53e-81: 298: 14.33		PCLO_HUMAN (2-750): 5.93e-20: 97.8: 10.23
+	Hs
		1066961 KIF14_HUMAN (41-700): 5.53e-81: 298: 14.33		CABIN_HUMAN (103-561): 3.85e-12: 72.2: 12.26
+	Hs
		497471 NEB2_HUMAN (1013-1151): 2.03e-20: 100: 31.29		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Ce
		136783 O17566_CAEEL (1099-1684): 9.47e-58: 222: 17.92		UNC89_CAEEL (1-345): 5.11e-15: 81.9: 10.11
+	Mm
		592771 NEB2_MOUSE (1013-1151): 1.76e-20: 100: 31.29		MTAP2_MOUSE (49-752): 4.26e-36: 149: 25.07
+	Mm
		1143421 DLG4_MOUSE (971-1245): 7.79e-30: 130: 17.10		ANK2_MOUSE (184-606): 1.18e-23: 109: 16.21
+	Mm
		581224 DLG4_MOUSE (971-1245): 7.79e-30: 130: 17.10		NFH_MOUSE (105-744): 4.06e-23: 107: 11.04
+	Mm
		1143433 DLG4_MOUSE (971-1245): 7.79e-30: 130: 17.10		SYNJ1_MOUSE (278-725): 9.45e-16: 83.9: 12.31
+	Mm
		581225 NEB2_MOUSE (1013-1151): 1.76e-20: 100: 31.29		NFH_MOUSE (105-744): 4.06e-23: 107: 11.04
+	Mm
		88458 DLG4_MOUSE (971-1245): 7.79e-30: 130: 17.10		D3Z656_MOUSE (377-751): 1.31e-09: 63.9: 12.53
+	Dm
		113067 M9NFI9_DROME (1006-1151): 7.04e-23: 109: 29.81		RPB1_DROME (243-604): 1.13e-09: 64.1: 13.85
+	Mm
		88462 NEB2_MOUSE (1013-1151): 1.76e-20: 100: 31.29		D3Z656_MOUSE (377-751): 1.31e-09: 63.9: 12.53