Interactor 1: PK3CD (O35904)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)
Gene: Pik3cd

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 23023391
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0010628 - positive regulation of gene expression
GO:0045087 - innate immune response
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1043
Mm

1 835
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024