HitPredict - High confidence protein-protein interactions

Interactor 1: COS (O16844)
Kinesin-like protein costa (Kinesin-like protein costal2)
Gene: COS

Interactor 2: COS (O16844)
Kinesin-like protein costa (Kinesin-like protein costal2)
Gene: COS

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	21844892, 22306085
Identification Methods	fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Kinesin~Kinesin
Common GO terms	GO:0003774 - cytoskeletal motor activity GO:0003777 - microtubule motor activity GO:0005119 - smoothened binding GO:0005524 - ATP binding GO:0005737 - cytoplasm and 20 others more... GO:0005829 - cytosol GO:0005871 - kinesin complex GO:0005874 - microtubule GO:0005875 - microtubule associated complex GO:0005929 - cilium GO:0007018 - microtubule-based movement GO:0007224 - smoothened signaling pathway GO:0007476 - imaginal disc-derived wing morphogenesis GO:0008017 - microtubule binding GO:0016887 - ATP hydrolysis activity GO:0019901 - protein kinase binding GO:0030707 - follicle cell of egg chamber development GO:0031625 - ubiquitin protein ligase binding GO:0035301 - Hedgehog signaling complex GO:0035591 - signaling adaptor activity GO:0042073 - intraciliary transport GO:0042981 - regulation of apoptotic process GO:0045879 - negative regulation of smoothened signaling pathway GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0140313 - molecular sequestering activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	1201
Dm

1	1201

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Last updated: 11Aug2025