HitPredict

Interactor 1: RRP8 (O43159)
Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1) (Nucleomethylin)
Gene: RRP8

Interactor 2: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 456 Hs			1 313
+	Hs
		196088 RRP8_HUMAN (1-456): 0: 700: 100.00		ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71
+	Hs
		196022 RRP8_HUMAN (1-456): 0: 700: 100.00		E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50
+	Hs
		196147 RRP8_HUMAN (1-456): 0: 700: 100.00		DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42
+	Hs
		196075 RRP8_HUMAN (1-456): 0: 700: 100.00		RED1_HUMAN (228-306): 5.95e-12: 68.4: 16.46
+	Hs
		196003 RRP8_HUMAN (1-456): 0: 700: 100.00		STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54