HitPredict

Interactor 1: O18332 (O18332)
FI01544p (Rab1)
Gene: Rab1

Interactor 2: ARL8 (Q9VHV5)
ADP-ribosylation factor-like protein 8 (Novel small G protein indispensable for equal chromosome segregation) (dGie)
Gene: ARL8

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0008089 - anterograde axonal transport GO:1904115 - axon cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 205 Dm			1 186
+	Hs
		974968 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		ARF6_HUMAN (10-183): 1e-84: 248: 33.91
+	Hs
		975232 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		ARF6_HUMAN (10-183): 1e-84: 248: 33.91
+	Hs
		956786 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RAB1B_HUMAN (17-184): 1.19e-68: 209: 20.35
+	Mm
		956826 RAB10_MOUSE (8-205): 5.24e-95: 276: 54.04		RAB1B_MOUSE (17-184): 2.39e-68: 208: 19.77
+	Hs
		956768 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RAB1C_HUMAN (17-184): 1.91e-66: 203: 19.77
+	Zm
		77342 B4FAE1_MAIZE (4-205): 3.4e-89: 262: 73.27		B4FAE1_MAIZE (17-184): 1.3e-70: 214: 20.93
+	Hs
		956703 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RAB14_HUMAN (17-186): 5.05e-65: 200: 15.52
+	Hs
		981254 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB1A_HUMAN (17-184): 8.65e-69: 209: 20.35
+	Hs
		981357 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB1B_HUMAN (17-184): 1.19e-68: 209: 20.35
+	Mm
		981416 RAB1A_MOUSE (1-205): 1.59e-90: 265: 82.93		RAB1B_MOUSE (17-184): 2.39e-68: 208: 19.77
+	Dm
		197051 O18332_DROME (1-205): 1.7e-90: 265: 100.00		ARF1_DROME (1-186): 3.66e-67: 204: 29.57
+	Hs
		956239 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB2A_HUMAN (15-186): 8.45e-66: 202: 15.91
+	Dm
		197031 O18332_DROME (1-205): 1.7e-90: 265: 100.00		RAB2_DROME (15-186): 3.89e-65: 200: 14.77
+	Hs
		957907 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB14_HUMAN (17-186): 5.05e-65: 200: 15.52
+	Hs
		981327 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB2B_HUMAN (15-186): 8.42e-65: 199: 15.34
+	Hs
		956483 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		RAB2A_HUMAN (15-186): 8.45e-66: 202: 15.91
+	Hs
		958022 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		RAB14_HUMAN (17-186): 5.05e-65: 200: 15.52
+	Hs
		1356536 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		RAB2B_HUMAN (15-186): 8.42e-65: 199: 15.34