HitPredict

Interactor 1: RAB2 (O18333)
Ras-related protein Rab-2 (EC 3.6.5.2)
Gene: RAB2

Interactor 2: ARF4 (P40945)
ADP ribosylation factor 4 (dARF II)
Gene: ARF4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0016192 - vesicle-mediated transport and 1 others more... GO:0046718 - symbiont entry into host cell
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Dm			1 180
+	Hs
		957905 RAB14_HUMAN (2-213): 7.34e-90: 264: 57.28		ARF6_HUMAN (5-179): 4.34e-74: 221: 64.57
+	Hs
		956237 RAB2A_HUMAN (1-213): 1.9e-87: 258: 89.67		ARF6_HUMAN (5-179): 4.34e-74: 221: 64.57
+	Hs
		974968 RAB1A_HUMAN (3-213): 1.3e-86: 255: 43.60		ARF6_HUMAN (5-179): 4.34e-74: 221: 64.57
+	Dm
		197048 O18332_DROME (3-213): 6.01e-91: 267: 45.50		ARF4_DROME (1-180): 7.78e-69: 208: 100.00
+	Hs
		974966 RB11A_HUMAN (3-213): 5.87e-85: 252: 46.45		ARF6_HUMAN (5-179): 4.34e-74: 221: 64.57
+	Dm
		197141 RAB2_DROME (1-213): 1.01e-91: 269: 100.00		ARF1_DROME (1-179): 2.92e-66: 202: 82.12
+	Hs
		957907 RAB14_HUMAN (2-213): 7.34e-90: 264: 57.28		RAB1A_HUMAN (3-180): 6.87e-68: 207: 19.67
+	Hs
		958022 RAB14_HUMAN (2-213): 7.34e-90: 264: 57.28		RAB1B_HUMAN (5-180): 8.47e-68: 206: 19.89
+	Hs
		981327 RAB2B_HUMAN (1-213): 1.64e-89: 263: 83.33		RAB1A_HUMAN (3-180): 6.87e-68: 207: 19.67
+	Hs
		1356536 RAB2B_HUMAN (1-213): 1.64e-89: 263: 83.33		RAB1B_HUMAN (5-180): 8.47e-68: 206: 19.89
+	Dm
		197051 O18332_DROME (3-213): 6.01e-91: 267: 45.50		ARF1_DROME (1-179): 2.92e-66: 202: 82.12
+	Zm
		77342 B4FAE1_MAIZE (3-213): 1.3e-87: 258: 44.08		B4FAE1_MAIZE (5-180): 1.07e-68: 209: 17.68
+	Hs
		956239 RAB2A_HUMAN (1-213): 1.9e-87: 258: 89.67		RAB1A_HUMAN (3-180): 6.87e-68: 207: 19.67
+	Hs
		956483 RAB2A_HUMAN (1-213): 1.9e-87: 258: 89.67		RAB1B_HUMAN (5-180): 8.47e-68: 206: 19.89
+	Hs
		981254 RAB1A_HUMAN (3-213): 1.3e-86: 255: 43.60		RAB1A_HUMAN (3-180): 6.87e-68: 207: 19.67
+	Hs
		612190 RB11A_HUMAN (3-213): 5.87e-85: 252: 46.45		ARF4_HUMAN (1-180): 2.88e-69: 209: 84.44
+	Hs
		956249 RAB2A_HUMAN (1-213): 1.9e-87: 258: 89.67		ARF1_HUMAN (1-180): 7.45e-67: 203: 81.11
+	Hs
		956433 RAB2A_HUMAN (1-213): 1.9e-87: 258: 89.67		RAB1C_HUMAN (5-180): 2.76e-66: 203: 18.79
+	Hs
		981357 RAB1A_HUMAN (3-213): 1.3e-86: 255: 43.60		RAB1B_HUMAN (5-180): 8.47e-68: 206: 19.89
+	Mm
		981416 RAB1A_MOUSE (3-213): 1.3e-86: 255: 43.60		RAB1B_MOUSE (5-180): 2.19e-67: 205: 19.89