HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26643866, 35676659
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 1215
+	Hs
		197427 SERA_HUMAN (1-533): 0: 667: 100.00		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		881167 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		1032389 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		881245 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1032538 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Mm
		292164 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		HDAC2_MOUSE (78-489): 8.71e-157: 479: 21.02
+	Hs
		880714 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		1032689 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Mm
		292177 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		HDAC7_MOUSE (440-891): 3.34e-145: 464: 36.59
+	Hs
		177284 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Hs
		1032674 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC9_HUMAN (7-432): 5.62e-136: 441: 33.19