HitPredict

Interactor 1: ADA12 (O43184)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
Gene: ADAM12

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	11313349, 25825872
Identification Methods	affinity chromatography technology, pull down, peptide array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 909 Hs			1 724
+	Hs
		655459 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		P85A_HUMAN (1-724): 0: 596: 100.00
+	Hs
		655355 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		P85A_HUMAN (1-724): 0: 596: 100.00
+	Hs
		314542 ATS2_HUMAN (5-900): 5.79e-101: 343: 16.58		P85A_HUMAN (1-724): 0: 596: 100.00
+	Hs
		433344 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		YES_HUMAN (568-724): 2.15e-31: 131: 20.61
+	Hs
		64622 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		RHG32_HUMAN (14-613): 1.13e-61: 227: 13.99
+	Hs
		147856 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		RHG33_HUMAN (14-325): 1.09e-56: 211: 19.02
+	Hs
		152229 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		YES_HUMAN (568-724): 2.15e-31: 131: 20.61