Interactor 1: IRAK2 (O43187)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)
Gene: IRAK2

Interactor 2: ZC12A (Q5D1E8)
Endoribonuclease ZC3H12A (EC 3.1.-.-) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A)
Gene: ZC3H12A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 21903422
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006954 - inflammatory response
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 625
Hs

1 599
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024