Protein: TAGL2
Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog)

Gene: TAGL2, TAGLN2
Organism: Homo sapiens
Interactions: 151
UniProt ID: P37802

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0007015 - actin filament organization
GO:0015629 - actin cytoskeleton
GO:0030855 - epithelial cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

790961

TAGL3
Transgelin-3

2

11

High-throughput

0.802

High

790883

ACTB
Actin, cytoplasmic 1

2

20

Small-scale

0.754

High

563340

CFTR
Cystic fibrosis transmembrane conductance regulator

3

7

High-throughput

0.643

High

389106

FINC
Fibronectin

1

3

High-throughput

0.618

High

618656

ML12A
Myosin regulatory light chain 12A

1

20

High-throughput

0.618

High

790888

ACTG
Actin, cytoplasmic 2

1

20

High-throughput

0.618

High

790889

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.618

High

790953

PARVA
Alpha-parvin

1

1

High-throughput

0.618

High

790959

TES
Testin

1

11

High-throughput

0.618

High

534729

BIP
Endoplasmic reticulum chaperone BiP

2

6

High-throughput

0.611

High

353052

AGR2
Anterior gradient protein 2 homolog

2

3

Small-scale

0.601

High

599169

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.586

High

240939

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

667595

CDK2
Cyclin-dependent kinase 2

2

6

High-throughput

0.584

High

790867

SYUA
Alpha-synuclein

2

5

Small-scale

0.584

High

790897

SQSTM
Sequestosome-1

2

4

High-throughput

0.584

High

790915

RICTR
Rapamycin-insensitive companion of mTOR

2

1

High-throughput

0.584

High

619564

VCAM1
Vascular cell adhesion protein 1

2

5

High-throughput

0.571

High

790880

TERA
Transitional endoplasmic reticulum ATPase

2

8

High-throughput

0.571

High

790890

SOS2
Son of sevenless homolog 2

2

1

High-throughput

0.571

High

790911

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

4

High-throughput

0.571

High

790927

DOCK8
Dedicator of cytokinesis protein 8

2

6

High-throughput

0.571

High

790945

ACE2
Angiotensin-converting enzyme 2

2

0

High-throughput

0.559

High

790916

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

790946

ARP6
Actin-related protein 6

1

20

High-throughput

0.553

High

790956

EHD2
EH domain-containing protein 2

1

4

High-throughput

0.541

High

135531

DNM1L
Dynamin-1-like protein

1

3

High-throughput

0.536

High

180731

TIF1A
Transcription intermediary factor 1-alpha

1

18

High-throughput

0.536

High

317141

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

5

High-throughput

0.536

High

361148

SODC
Superoxide dismutase [Cu-Zn]

1

3

High-throughput

0.536

High

729653

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

787908

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

790928

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.536

High

790944

TX101
Testis-expressed protein 101

1

2

High-throughput

0.536

High

588072

RFA2
Replication protein A 32 kDa subunit

2

9

High-throughput

0.533

High

694787

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

7

High-throughput

0.533

High

767567

RFA3
Replication protein A 14 kDa subunit

2

8

High-throughput

0.533

High

790931

FNDC8
Fibronectin type III domain-containing protein 8

1

0

High-throughput

0.517

High

538893

EPB41
Protein 4.1

1

5

High-throughput

0.515

High

790877

DYN2
Dynamin-2

1

3

High-throughput

0.515

High

790930

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

3

High-throughput

0.515

High

790957

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.513

High

421623

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

790868

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

790870

HD
Huntingtin

1

0

High-throughput

0.493

High

790907

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

133454

ACATN
Acetyl-coenzyme A transporter 1

1

1

High-throughput

0.489

High

583485

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

2

High-throughput

0.489

High

674095

BRD2
Bromodomain-containing protein 2

1

4

High-throughput

0.489

High

790940

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

3

High-throughput

0.489

High

125287

LEG9
Galectin-9

1

2

High-throughput

0.479

High

131777

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

7

High-throughput

0.479

High

176154

PER2
Period circadian protein homolog 2

1

2

Small-scale

0.479

High

247243

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

9

High-throughput

0.479

High

271948

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

345454

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

7

High-throughput

0.479

High

377435

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

3

High-throughput

0.479

High

379914

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.479

High

385515

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.479

High

400402

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.479

High

487028

PARP1
Poly [ADP-ribose] polymerase 1

1

13

High-throughput

0.479

High

555919

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

565199

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

659382

CRCM
Colorectal mutant cancer protein

1

5

High-throughput

0.479

High

700568

PSA5
Proteasome subunit alpha type-5

1

1

Small-scale

0.479

High

790869

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

790871

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

790873

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

790875

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

790881

RAB25
Ras-related protein Rab-25

1

6

High-throughput

0.479

High

790882

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

2

High-throughput

0.479

High

790885

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

790886

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.479

High

790887

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

790892

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

3

High-throughput

0.479

High

790893

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

11

High-throughput

0.479

High

790896

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

790898

CUL3
Cullin-3

1

5

High-throughput

0.479

High

790899

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.479

High

790900

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

6

High-throughput

0.479

High

790902

CUL7
Cullin-7

1

2

High-throughput

0.479

High

790903

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.479

High

790904

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

790905

PCBP1
Poly(rC)-binding protein 1

1

1

Small-scale

0.479

High

790912

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.479

High

790913

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

790914

CDC73
Parafibromin

1

2

High-throughput

0.479

High

790917

5MP2
eIF5-mimic protein 2

1

1

High-throughput

0.479

High

790919

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

2

High-throughput

0.479

High

790920

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

790932

NUDC2
NudC domain-containing protein 2

1

4

High-throughput

0.479

High

790933

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

790934

TOPB1
DNA topoisomerase 2-binding protein 1

1

5

High-throughput

0.479

High

790935

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

8

High-throughput

0.479

High

790936

REQU
Zinc finger protein ubi-d4

1

5

High-throughput

0.479

High

790938

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.479

High

790941

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

790943

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.479

High

790948

ATG5
Autophagy protein 5

1

2

High-throughput

0.479

High

790952

DUS22
Dual specificity protein phosphatase 22

1

5

High-throughput

0.479

High

790955

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

790960

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

790964

TRAF6
TNF receptor-associated factor 6

1

17

High-throughput

0.479

High

583212

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

702887

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

790891

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

790894

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

790909

PWP3A
PWWP domain-containing DNA repair factor 3A

1

0

High-throughput

0.458

High

790929

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

790951

MYOZ1
Myozenin-1

1

0

High-throughput

0.458

High

790958

TRM7
tRNA

1

0

High-throughput

0.458

High

790962

CFA45
Cilia- and flagella-associated protein 45

1

0

High-throughput

0.458

High

790884

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.457

High

184597

MK13
Mitogen-activated protein kinase 13

1

13

Small-scale

0.445

High

591509

H2AX
Histone H2AX

1

1

High-throughput

0.445

High

765191

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.445

High

790939

NUDC1
NudC domain-containing protein 1

1

2

High-throughput

0.445

High

790947

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

4

High-throughput

0.445

High

217908

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

239759

PCDH7
Protocadherin-7

1

1

High-throughput

0.437

High

297486

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.437

High

324605

HEXI1
Protein HEXIM1

1

1

High-throughput

0.437

High

355439

NSD2
Histone-lysine N-methyltransferase NSD2

1

4

Small-scale

0.437

High

371348

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.437

High

606343

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.437

High

685430

U2AF2
Splicing factor U2AF 65 kDa subunit

1

4

High-throughput

0.437

High

790874

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

790878

CDK9
Cyclin-dependent kinase 9

1

16

High-throughput

0.437

High

790879

EFNB2
Ephrin-B2

1

1

High-throughput

0.437

High

790895

RFA4
Replication protein A 30 kDa subunit

1

9

High-throughput

0.437

High

790901

MDC1
Mediator of DNA damage checkpoint protein 1

1

4

High-throughput

0.437

High

790906

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.437

High

790910

DUS28
Dual specificity phosphatase 28

1

5

High-throughput

0.437

High

790918

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

790921

GOLI
E3 ubiquitin-protein ligase RNF130

1

4

High-throughput

0.437

High

790922

SLX4
Structure-specific endonuclease subunit SLX4

1

7

High-throughput

0.437

High

790923

NIN
Ninein

1

14

High-throughput

0.437

High

790926

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.437

High

790949

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.437

High

790950

DUS21
Dual specificity protein phosphatase 21

1

6

High-throughput

0.437

High

790954

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

790963

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

516649

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

4

High-throughput

0.407

High

790908

TIGD6
Tigger transposable element-derived protein 6

1

0

High-throughput

0.279

Low

790942

ELOV1
Very long chain fatty acid elongase 1

1

0

High-throughput

0.279

Low

254543

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.269

Low

790872

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low

790876

DNLI4
DNA ligase 4

1

0

High-throughput

0.249

Low

790924

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

790925

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

790937

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025