Interactor 1: IRAK2 (O43187)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)
Gene: IRAK2

Interactor 2: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 21903422
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0060090 - molecular adaptor activity
GO:0070498 - interleukin-1-mediated signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 625
Hs

1 274
+ Hs
+ Mm

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Last updated: 15 Jul 2024