HitPredict

Interactor 1: PSMD3 (O43242)
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)
Gene: PSMD3

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 27114451
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 534 Hs			1 624
+	Hs
		198754 PSMD3_HUMAN (1-534): 0: 642: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Mm
		539514 PSMD3_MOUSE (1-534): 0: 633: 96.26		UBQL2_MOUSE (1-624): 1.66e-145: 437: 84.01
+	Hs
		198730 PSMD3_HUMAN (1-534): 0: 642: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Dm
		627146 PSMD3_DROME (40-533): 0: 562: 57.49		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		198677 PSMD3_HUMAN (1-534): 0: 642: 100.00		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		198650 PSMD3_HUMAN (1-534): 0: 642: 100.00		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		198601 PSMD3_HUMAN (1-534): 0: 642: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27