Interactor 1: HEM2 (O26839)
Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)
Gene: hemB
Interactor 2: HEM2 (O26839)
Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)
Gene: hemB
Species: Methanothermobacter thermautotrophicus str. Delta H
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16037073 |
| Identification Methods | blue native page |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ALAD~ALAD |
| Common GO terms | GO:0004655 - porphobilinogen synthase activity GO:0005829 - cytosol GO:0006782 - protoporphyrinogen IX biosynthetic process GO:0008270 - zinc ion binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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| + | Mm |   |
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| + | Ec | |
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| + | Dm | |
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| + | Sc | |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
