Protein: HEM2
Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)

Gene: HEM2, hemB
Organism: Escherichia coli K-12
Interactions: 16
UniProt ID: P0ACB2

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004655 - porphobilinogen synthase activity
GO:0005829 - cytosol
GO:0006782 - protoporphyrinogen IX biosynthetic process
GO:0006783 - heme biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

498964

HEM2
Delta-aminolevulinic acid dehydratase

1

4

High-throughput

0.618

High

498971

FTSY
Signal recognition particle receptor FtsY

1

0

High-throughput

0.513

High

498974

RIHA
Pyrimidine-specific ribonucleoside hydrolase RihA

1

0

High-throughput

0.513

High

498965

DBHA
DNA-binding protein HU-alpha

1

1

High-throughput

0.479

High

498966

AHPC
Alkyl hydroperoxide reductase C

1

1

High-throughput

0.479

High

490146

CH10
Co-chaperonin GroES

1

0

High-throughput

0.458

High

498972

PPSA
Phosphoenolpyruvate synthase

1

0

High-throughput

0.458

High

498976

GRCA
Autonomous glycyl radical cofactor

1

0

High-throughput

0.458

High

498968

HISJ
Histidine-binding periplasmic protein

1

0

High-throughput

0.279

Low

498969

SANA
Protein SanA

1

0

High-throughput

0.279

Low

498975

FADH
2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

1

0

High-throughput

0.279

Low

393923

PBPB
Penicillin-binding protein 1B

1

0

High-throughput

0.261

Low

498967

CPXP
Periplasmic protein CpxP

1

0

High-throughput

0.261

Low

498970

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.249

Low

498973

DEGQ
Periplasmic pH-dependent serine endoprotease DegQ

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025