Protein: HEM2
Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)

Gene: HEM2
Organism: Saccharomyces cerevisiae S288C
Interactions: 20
UniProt ID: P05373

Gene Ontology (top 5):
GO:0004655 - porphobilinogen synthase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006782 - protoporphyrinogen IX biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

427972

HEM2
Delta-aminolevulinic acid dehydratase

2

4

High-throughput

0.791

High

427977

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

427988

IMA1
Importin subunit alpha

1

0

High-throughput

0.518

High

427973

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

391966

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

427981

TOR1
Serine/threonine-protein kinase TOR1

1

0

High-throughput

0.460

High

427984

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

427978

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

427979

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

427980

TMT1
Trans-aconitate 3-methyltransferase

1

0

High-throughput

0.458

High

427983

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

427987

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

427989

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

427974

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

427975

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

427976

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

427986

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

427985

TEM1
Protein TEM1

1

0

High-throughput

0.282

High

427982

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025