HitPredict

Interactor 1: SUV91 (O43463)
Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) (Position-effect variegation 3-9 homolog) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
Gene: SUV39H1

Interactor 2: Q15156 (Q15156)
PML-RAR protein
Gene: PML-RAR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16449642
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 797
+	Hs
		203617 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		RARA_HUMAN (350-797): 2.03e-106: 336: 90.40
+	Hs
		203613 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		203631 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		PML_HUMAN (1-413): 7.06e-89: 301: 96.37
+	Hs
		203673 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		NR1H3_HUMAN (397-753): 4.89e-83: 274: 31.30
+	Hs
		203618 SUV91_HUMAN (1-412): 2.55e-163: 467: 100.00		THA_HUMAN (423-727): 9.32e-60: 212: 37.46
+	Hs
		782635 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29
+	Hs
		782659 EHMT1_HUMAN (112-408): 1.23e-80: 271: 32.13		HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29
+	Hs
		370223 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		370465 EHMT1_HUMAN (112-408): 1.23e-80: 271: 32.13		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		668912 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		PML_HUMAN (1-413): 7.06e-89: 301: 96.37
+	Mm
		1142741 EHMT2_MOUSE (81-408): 6.88e-84: 280: 31.58		ERR2_MOUSE (405-752): 2.18e-90: 293: 29.02
+	Hs
		488013 NSD1_HUMAN (123-411): 2.72e-65: 228: 24.14		RARA_HUMAN (350-797): 2.03e-106: 336: 90.40
+	Mm
		1125427 EHMT1_MOUSE (75-408): 5.46e-78: 264: 31.29		ERR2_MOUSE (405-752): 2.18e-90: 293: 29.02
+	Hs
		1269380 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83
+	Hs
		370370 SETD2_HUMAN (87-411): 1.48e-67: 234: 24.26		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		370224 NSD1_HUMAN (123-411): 2.72e-65: 228: 24.14		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Mm
		93590 SETD2_MOUSE (87-411): 1.2e-66: 232: 23.67		ERR2_MOUSE (405-752): 2.18e-90: 293: 29.02
+	Hs
		1269543 SETD2_HUMAN (87-411): 1.48e-67: 234: 24.26		ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83
+	Hs
		490071 NSD1_HUMAN (123-411): 2.72e-65: 228: 24.14		NR2F6_HUMAN (391-756): 5.17e-86: 280: 27.81
+	Hs
		975467 EHMT2_HUMAN (81-408): 1.21e-82: 276: 31.58		PPARD_HUMAN (423-751): 6.43e-46: 172: 31.35