Protein: SODC
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)

Gene: SODC, SOD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P00445

Gene Ontology (top 5):
GO:0004784 - superoxide dismutase activity
GO:0005507 - copper ion binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

361442

CCS1
Superoxide dismutase 1 copper chaperone

9

9

Small-scale

0.968

High

361438

DUN1
DNA damage response protein kinase DUN1

2

1

Small-scale

0.639

High

361420

KC11
Casein kinase I homolog 1

2

2

Small-scale

0.621

High

361415

BIP
Endoplasmic reticulum chaperone BiP

2

2

High-throughput

0.588

High

361458

SMT3
Ubiquitin-like protein SMT3

2

3

Small-scale

0.586

High

359093

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

2

3

Small-scale

0.584

High

361395

SODC
Superoxide dismutase [Cu-Zn]

1

10

Small-scale

0.575

High

361416

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.536

High

361417

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.536

High

361418

FKBP
FK506-binding protein 1

1

3

High-throughput

0.536

High

361431

MAC1
Metal-binding activator 1

1

0

Small-scale

0.529

High

361422

YJU2
Splicing factor YJU2

1

0

High-throughput

0.513

High

361435

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

High-throughput

0.481

High

361459

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.481

High

361444

BNI1
Protein BNI1

1

0

High-throughput

0.480

High

361454

FRDA
Frataxin homolog, mitochondrial

1

0

Small-scale

0.480

High

358914

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

3

High-throughput

0.479

High

361397

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.479

High

361398

ENO1
Enolase 1

1

5

High-throughput

0.479

High

361399

ENO2
Enolase 2

1

5

High-throughput

0.479

High

361400

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.479

High

361401

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

361402

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.479

High

361403

HXKA
Hexokinase-1

1

1

High-throughput

0.479

High

361404

HXKB
Hexokinase-2

1

1

High-throughput

0.479

High

361414

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

361419

TKT1
Transketolase 1

1

1

High-throughput

0.479

High

361421

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

361424

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

361427

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

361429

TSA1
Peroxiredoxin TSA1

1

5

High-throughput

0.479

High

361434

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

361436

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

361445

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

361448

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

361452

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

361430

TOR1
Serine/threonine-protein kinase TOR1

1

0

High-throughput

0.460

High

361450

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.460

High

360912

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.458

High

361405

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

361407

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.458

High

361412

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

361413

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

361423

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

361437

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

361440

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

361443

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

361446

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

361447

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

361457

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

361449

ARK1
Actin-regulating kinase 1

1

2

High-throughput

0.457

High

361409

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

361410

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

361411

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

361425

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

361441

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

361433

ARPC1
Actin-related protein 2/3 complex subunit 1

1

2

High-throughput

0.437

High

361451

COFI
Cofilin

1

1

High-throughput

0.437

High

361455

AP3D
AP-3 complex subunit delta

1

4

High-throughput

0.437

High

361432

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

Small-scale

0.426

High

361406

CALM
Calmodulin

2

0

High-throughput

0.324

High

361428

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

361439

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.282

High

361408

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.279

Low

361453

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

361456

GID12
GID complex associated protein 12

1

0

High-throughput

0.269

Low

361396

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

361426

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025