HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29568061, 11208159, 35696571
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 798
+	Hs
		403898 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		205020 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		205006 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITB4_HUMAN (11-727): 0: 566: 33.65
+	Hs
		574544 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		396592 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ITB3_HUMAN (25-797): 0: 646: 44.02
+	Hs
		574558 TITIN_HUMAN (18-351): 1.31e-09: 62.9: 10.41		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		639911 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		ITB7_HUMAN (31-796): 0: 615: 43.36
+	Hs
		205064 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32
+	Hs
		206100 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Dm
		247340 NBEA_DROME (93-391): 4.41e-33: 134: 10.82		TENM_DROME (336-619): 2.72e-36: 150: 15.91
+	Hs
		205299 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26
+	Hs
		205154 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80
+	Dm
		247138 Q9VPR2_DROME (16-395): 2.38e-10: 64.9: 9.92		TENM_DROME (336-619): 2.72e-36: 150: 15.91