HitPredict

Interactor 1: TGON2 (O43493)
Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)
Gene: TGOLN2

Interactor 2: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 377
+	Hs
		203208 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00
+	Hs
		205074 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		P85A_HUMAN (241-376): 1.37e-22: 101: 19.57
+	Hs
		204925 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		FYN_HUMAN (7-173): 7.47e-21: 96: 15.39
+	Hs
		205432 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07
+	Mm
		1113250 MYCB2_MOUSE (17-437): 1.51e-49: 183: 12.66		SRBS2_MOUSE (46-288): 1.38e-24: 107: 18.85
+	Hs
		205251 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		206084 TGON2_HUMAN (1-437): 1.03e-62: 210: 100.00		ITSN2_HUMAN (7-85): 2.68e-12: 70.6: 24.05
+	Hs
		924632 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Rn
		192744 SYNJ1_RAT (24-384): 5.32e-11: 67.2: 10.24		SRBS2_RAT (3-162): 4.86e-25: 109: 28.05
+	Hs
		782795 TENS2_HUMAN (9-345): 1.68e-22: 102: 14.33		CSK_HUMAN (4-143): 1.92e-12: 70.2: 14.38
+	Hs
		203192 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		SRBS2_HUMAN (64-287): 1.79e-23: 104: 18.26
+	Hs
		203230 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		SH319_HUMAN (8-254): 6.26e-19: 90.5: 19.84
+	Hs
		522749 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32
+	Hs
		554292 MUC1_HUMAN (17-398): 8.52e-13: 72.6: 9.42		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		517796 NFH_HUMAN (76-385): 7.1e-12: 69.5: 13.78		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		203228 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07
+	Hs
		203218 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		924760 PRG4_HUMAN (86-391): 4.16e-10: 64.1: 8.77		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		203241 SYNJ1_HUMAN (17-393): 3.24e-10: 64.5: 9.60		SH3K1_HUMAN (58-207): 2.14e-09: 61.3: 17.76